Kemal KİRAZ, Selahattin AKYOL, Mustafa ÇÖRTÜK, Alaa QUİSİ, Ömer POYRAZ

Amlodipinin çok nadir bir yan etkisi: Kardiyojenik olmayan pulmoner ödem

Kalsiyum kanal blokerleri kardiyovasküler tıpta en çok kullanılan ilaçlar arasındadır. Hem düşük maliyetli, hem de günde bir kez kullanılan amlodipin, en sık reçete edilen ilaçlardan biridir. Periferik ödem amlodipinin iyi bilinen bir yan etkisi ise de amlodipin ile ilişkili kardiyojenik olmayan pulmoner ödem çok nadirdir. Bu yazıda, intihar amacıyla 300 mg amlodipini oral yoldan alan, kardiyojenik olmayan pulmoner ödemli 24 yaşında bir kadın olgu sunuldu. Hasta sıvı replasmanı, inotropik ajanlar ve mekanik ventilasyon ile başarı ile tedavi edildi. Bildiğimiz kadarı ile bu Türkiye’de sunulan ilk olgudur.

A very rare side effect of amlodipine: non-cardiogenic pulmonary edema

Calcium channel blockers are among the most widely used drugs in cardiovascular medicine. Amlodipine, which is both cost-effective and taken once daily, is one of the most commonly prescribed agents. Although peripheral edema is a well-known side effect of amlodipine, non-cardiogenic pulmonary edema associated with amlodipine is very rare. Herein, we describe a 24-year-old female case of non-cardiogenic pulmonary edema after ingestion of 300 milligram of amlodipine orally for a suicide attempt. The patient was successfully treated with fluid replacement, inotropic drugs, and mechanically ventilation. To the best of our knowledge, this is the first case reported in Turkey.

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