Endobronchial treatment of benign endobronchial neoplasms: Our 10 years of experience
Background: The aim of the study was to assess the safety, efficacy, complications, and long-term outcomes of endobronchial treatment for benign endobronchial tumors. Methods: A total of 53 patients (39 males, 14 females; mean age: 53.7 years; range, 12 to 83 years) with the diagnosis of benign endobronchial neoplasms in our center between November 2010 and September 2019 were retrospectively analyzed. Data including demographic and clinical characteristics of the patients and treatment outcomes were examined. Results: Tumors regressed in all patients with argon plasma coagulation, diode laser and electrocautery, which was combined with cryotherapy in some cases. Complications were observed in five (9%) patients. Major complications were atrial fibrillation in two patients and respiratory failure requiring mechanical ventilation in one patient. Minor complications were minimal bleeding in two patients. The response was very good in 39 (74%) patients and good in 12 (23%) patients. There was no significant difference in the residual tissue formation requiring cryotherapy among the endobronchial treatment modalities (p>0.05). The five-year survival rate was 94%. No endobronchial treatment-related mortality was observed in any of the patients. Conclusion: Endobronchial treatment modalities including diode laser, electrocautery, and argon plasma coagulation combined with or without cryotherapy are effective and safe in the treatment of benign endobronchial tumors. Keywords: Argon plasma coagulation,
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- 1. Sardaro A, Bardoscia L, Petruzzelli MF, Portaluri M. Epithelioid hemangioendothelioma: an overview and update on a rare vascular tumor. Oncol Rev 2014;8:259.
- 2. Dail DH, Liebow AA. Intravascular bronchioloalveolar tumor. Am J Pathol 1975;78:6a-7a.
- 3. Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer 1982;50:970-81.
- 4. Gómez-Arellano LI, Ferrari-Carballo T, Domínguez-Malagón HR. Multicentric epithelioid hemangioendothelioma of bone. Report of a case with radiologic-pathologic correlation. Ann Diagn Pathol 2012;16:43-7.
- 5. Lam KY, Dickens P, Chan AC. Tumors of the heart. A 20-year experience with a review of 12,485 consecutive autopsies. Arch Pathol Lab Med 1993;117:1027-31.
- 6. Roberts WC. Primary and secondary neoplasms of the heart. Am J Cardiol 1997;80:671-82.
- 7. Reynen K. Cardiac myxomas. N Engl J Med 1995;333:1610-7.
- 8. Sugimoto T, Yamamoto K, Yoshii S. A Primary Epithelioid Hemangioendothelioma of the Right Atrium: Report of a Case and Literature Review. Open Journal of Thoracic Surgery 2013;3:63-7.
- 9. Hayward RH, Korompai FL. Endothelioma of the mitral valve. Ann Thorac Surg 1979;28:87-9.
- 10. Lisy M, Beierlein W, Müller H, Bültmann B, Ziemer G. Left atrial epithelioid hemangioendothelioma. J Thorac Cardiovasc Surg 2007;133:803-4.