Dev mediastinal tümörlerin cerrahi tedavisi

Amaç: Bu çalışmada dev mediastinal tümörlerinin cerrahi tedavi sonuçları değerlendirildi. Çalışma planı: Temmuz 2013-Temmuz 2018 tarihleri arasında dev mediastinal tümör nedeniyle merkezimizde radikal cerrahi yapılan toplam 31 hastanın (26 erkek, 5 kadın; ort. yaş 27.7±8.2 yıl; dağılım, 18-56 yıl) ve Ulusal Biyoteknoloji Bilgi Merkezi veri tabanından alınan 47 dev mediastinal tümör olgusu (26 erkek, 21 kadın; ort. yaş 45.4±16.7 yıl; dağılım, 19-62 yıl) retrospektif olarak incelendi. Hastaların iki yıllık genel sağkalımları ve hastalıksız sağkalımları değerlendirildi. Bulgular: Hastaların tümüne radikal cerrahi (R0 rezeksiyon) yapıldı. Dev mediastinal tümörlerin neden olduğu semptomlar, radikal cerrahi sonrasında takip sırasında geriledi. İki yıllık genel sağkalım ve hastalıksız sağkalım oranları sırasıyla %100 ve %86.7 olup, iyi prognozun göstergesi idi. Malignitelerin cerrahi işlemleri, benign patolojilerinkinden daha zor idi. Sonuç: Radikal cerrahi, adjuvan tedaviden bağımsız olarak, kısa sürede semptomları rahatlatmak ve iki yıla varana kadar iyi bir prognoz elde etmek için, dev mediastinal tümörlerin tedavisinin temelini oluşturur. Komplikasyonları azaltmak için radikal cerrahi öncesinde, cerrahi rol titizlikle planlanmalıdır.

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