Ertuğrul ÇELİK, Sedat GÜRKÖK, Hasan ÇAYLAK, Ersin SAPMAZ, Kuthan KAVAKLI

Atypical carcinoid tumor of the thymus: two case reports

Timusun nöroendokrin hücrelerinden köken alan timusun karsinoid tümörlerine çok nadir rastlanır. Erkeklerde üç kat daha fazla görülür. Klinik olarak timik atipik kasinoid tümörler, tipik karsinoid tümörlerden daha agresif bir davranış sergiler. Hastalıksız sağkalım oranı genellikle kötüdür. Tedavide birinci seçenek, tümörsüz rezeksiyon sınırlarının elde edildiği geniş rezeksiyondur. Radyoterapi ve kemoterapinin etkinliği halen belirsizdir. Bu yazıda, birinde adrenal yetmezliğin, diğerinde ise Cushing hastalığının eşlik ettiği atipik karsinoid tümörlü iki olgu sunuldu.

Timusun atipik karsinoid tümörü: İki olgu sunumu

Carcinoid tumors of thymus originating from neuroendocrine cells of thymus are seen very rarely. It is three times more in male. Clinically, thymic atypical carcinoid tumor demonstrates a more aggressive course than thymic typical carcinoid tumor. The disease-free survival rate is usually worse. The primary choice of treatment is extended resection which should be achieved tumor-free resection margins. The efficacy of radiotherapy and chemotherapy is still unclear. In this article, we present two cases who had atypical carcinoid tumor with adrenal insufficiency in one and Cushing disease in other.

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