Volkan TÜRÜNZ, Faruk MERİÇ, İsmail TOPÇU

Tip 2 Diabetes Mellitusta HbA1c Düzeyi ile Beyin Sapı Odyometrisinin Karşılaştırılması ve Prognoz Tayinindeki Yeri

Giriş: Son yüzyılda diabetes mellitus (DM) mortalite ve morbidite açısından en önemli hastalıklardan biri olmuştur. Diabetes mellitusun komplikasyonlarından korunmak için subklinik nörapatiyi düzenli aralıkla Auditory Brainstem Response (ABR) kaydı yaparak tespit etmek mümkündür. ABR kaydında herhangi bir patoloji saptanırsa hastaların kan şekeri daha sıkı takip edilmeli ve hastalar özellikle hipoglisemi ve ketoasidozdan korunmalıdır. Materyal-Metod: Poliklinik kontrollerinde hastaların açlık kan şekeri takibi yanı sıra kan HbA1c kontrolleri yapılarak son 3 aylık kan şekeri hakkında bilgi sahibi olunabilir. Hastaların kan şekerindeki aşırı dalgalanmalara izin verilmemeli mümkünse hastalar evde kendileri kan şekerlerini günde birkaç defa ölçerek kaydetmelidirler. Hastaların yaşlarına göre ABR kayıtlarının karşılaştırması yapılarak belirli aralıklarla tekrarlanması hastaların monitörizasyonu açısından çok önemlidir. Bulgular: Çalışmamızda diabetes mellituslu 30 hasta ile 30 kontrol gurubunun kan HbA1c düzeyleri ile uyarlanmış beyin sapı cevapları karşılaştırılmıştır. Her iki grup arasında I, III ve V dalga latansları ile I-III, I-V ve III-V interpik dalga latansları arasında istatistiksel olarak kayda değer fark bulunmamıştır. Litaratürde de benzer şekilde sonuçlar elde edilmiştir; fakat nöropati olan hastalarda belirgin uzama saptanmıştır. Ayrıca biz diabet süresi ve kan HbA1c düzeyi ile dalga latansları arasında kayda değer ilgi saptamışken (p<0.05) literatürde diabet süresi ve kan Hb A1c ile kayda değer ilgi saptanmamıştır. Sonuç: Sonuç olarak diabet komplikasyon yapmadan önce latent bir period gösterir ve bu periodda elektrofizyolojik testlerle olası komplikasyonlar önceden tespit edilebilir ve önceden tedbir alınabilir. ABR bu nedenle iyi bir monitorizasyon sağlayabilir. Anahtar kelimeler: Diabetes mellitus, HbA1c, ABR, BERA, Odyometri.

Anahtar Kelimeler:

Diabetes mellitus, HbA1c, ABR, BERA, Odyometri.

Comparing the HbA1c levels in Type 2 Diabetes Mellitus Discase and Brain Stem Odyometry and The Role in Prognoais

Introduction: Most recently, it was accepted that diabetes mellitus (DM) is the most important disease from the point of view mortality and morbidity. It is possible to determine subclinic neuropathy recording Auditory Brainstem Response (ABR) to avoid complication of DM. If it is determined pahtological condition on the ABR recording, it must be followed more tightly serum glucose levels of patients and it must be avoided especially hipoglisemia and ketoasidosis. It can be obtained information about last three monthly blood glucose controlling HbA1c levels of patients together with fasting blood glucose following in the outpatient controls. It should not give permission excessive undolation of blood glucose patients must be recorded assaying several times their blood glucose. It is important that ABR records of patients must be compared according to ages repeating with spesific intervals. Materials and Methods: In our study, it was compared evoked brainstem responces with serum HbA1c levels of 30 patients with Diabetes Mellitus and 30 control group patients when working groups compared with respect whether I, III and V wave latences. Results: No statistical difference was found between groups that examined. It was observed smilar results to our study, it was determined clear axtend on the patients with neuropathy. Statistically significance was found between diabetes period and serum HbA1c levels with wave latences (p<0.05) but no difference was found in diabetes period when compare to the serum HbA1c levels in the literature. Conclusion: Diabetes Mellitus is the disease showing a latent period before complications of DM and it is possible to determine complications of DM using electrophysiological tests in this period and to take measures. For this reason, ABR can provide a good monitorisation. Key words: Diabetes mellitus, HbA1c, ABR, BERA, Odiometry.

Keywords:

Diabetes mellitus, HbA1c, ABR, BERA, Odiometry.,

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