Hüseyin YILDIRIM, Muzaffer METİNTAŞ, Sinan ERGİNEL, İrfan UÇGUN, Füsun ALATAŞ, Ragıp ÖZKAN

Üç olgu nedeniyle Wegener granülomatözü

Wegener granülomatözü (WG), üst ve alt solunum yolları ile böbreği tutabilen, çok sistem tutulumla granülomatöz vaskülitis ile karakterize bir hastalıktır. Tanı konulması geciktiğinde mortal seyreden bir hastalık olan WG'nin, kliniğimize değişik ön tanılarla başvuran ve yapılan incelemeler sonucu WG tanısı konularak tedavi başlanan ve takibe alınan üç olgunun sunularak literatür eşliğinde tartışılması amaçlanmıştır. Üç olguda da klinik, radyolojik ve patolojik bulgularla WG tanısı kondu. c-AHCA iki olguda pozitif, bir olguda ise negatifti. Bir olguda tedaviyle tam remisyon sağlandı. Bir olgunun tedavisi devam etmekte, bir olgumuz ise kontrolümüz dışında olduğundan prognozu izlenemedi.

Wegener granulomatosis: Three cases

Wegener granulomatosis (WG) is characterized by granulomatous vasculitis that involves multisystem, including upper and lower airways and kidney. WG may be a mortal disease if the diagnosis is delayed. The aim of this study is to present three patients admitted with different prediagnosis but after the investigations were diagnosed as WG and followed in our clinic. The cases were discussed with the literature knowledge. All three patients were diagnosed as WG with clinical, radiological and pathological findings. c-AHCA was positive in two patients, and negative one. Complete remission was established with treatment in one case. The treatment of other patients going on, however, the third patient was lost to follow up.

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