Ferda ÖNER, Özlem GÜRKAN, Gülseren KARABIYIKOĞLU, Sevgi SARYAL, Öznur AKKOCA

The relationship between dyspnea and pulmonary functions, arterial blood gases and exercise capacity in patients with COPD

Dispne, solunum güçlüğünün hissedilmesi olarak tanımlanır. "Medical Research Council (MRC)" skalası, "Baseline Dyspnea Index (BDI)" ve Borg skalası dispnenin derecelendirilmesi için kullanılan klinik yöntemlerdir. Bu çalışmanın amacı, kronik obstrüktif akciğer hastalıklarında (KOAH) klinik dispne skalaları ile solunum fonksiyonları, egzersiz kapasitesi arasındaki ilişkiyi araştırmaktı. Yirmi KOAH'lı olgu ve 12 sağlıklı kontrol olgusu çalışmaya alındı. Tüm olgulara MRC skalası, BDI ve Borg skalası uygulandı. Solunum fonksiyon testleri, maksimal inspiratuvar basınç (Pimax), ağız içi tıkanma basıncı (P0.1), solunum paterni (SP), arter kan gazları ve semptom-sınırlı bisiklet egzersiz testi yapıldı. KOAH olgularının tümü dispne nedeniyle testi sonlandırdılar. KOAH olguları orta şiddetli grupta yer alıyordu (ortalama FEV1: %56.00 ± 15.03). Klinik dispne skalaları; MRC skalası: 2.10 ± 0.55, BDI: 5.65 ± 1.60 ve Borg skalası: 4.55 ± 1.23 idi. BDI Pimax ve P0.1 ile ilişkili değilken, hava akım hızları, PaO2 ve SaO2 ile (p< 0.05, p< 0.01); Borg skalası ise hava akım hızlarıyla anlamlı derecede ilişkiliydi (p< 0.01). Diğer dispne skalaları egzersiz testi parametreleriyle ilişkili değilken, sadece MRC skalası ise pik oksijen tüketimi (VO2/kg%) ile önemli derecede ilişkiliydi (p< 0.05). Sonuç olarak, bu çalışmada klinik dispne skalalarının ve egzersiz dispne skalasının özellikle hava akım hızları ve AKG ile ilişkili olduğu gösterildi. Fakat bu skalalar egzersiz kapasitesiyle anlamlı derecede ilişkili değildi.

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