Haluk Celalettin ÇALIŞIR, Aylin BABALIK

Multidrug resistant tuberculosis with multiple organ involvement

Çok ilaca dirençli tüberküloz durumu, klinikte tedavisi ve yönetimi oldukça güç tablolar oluşturmaktadır. Bakteri popülasyonunun az olduğu lezyonlarda direnç gelişme olasılığı düşüktür. Bu olgu skrotal kitle ile başvuran hastalarda infertiliteye sebep olabilen genital tüberkülozun akılda tutulması gerektiğini vurgulamak ve nadir görülen bir ekstrapul- moner tutulumlu bir pulmoner çok ilaca dirençli tüberküloz olgusu olduğu için sunulmuştur.

Çoklu organ tutulumu ile seyreden çok ilaca dirençli tüberküloz

Multidrug resistant tuberculosis has been a challenging situation in the clinical practice with respect to appropriate clini- cal treatment and management of the disease. The likelihood of resistance development is known to be lower in lesions with lesser percentages of the bacterial population. The present paper was designed to present a rare case of pulmonary multidrug resistant tuberculosis with extrapulmonary involvement to emphasize the consideration of genital tuberculosis with possible infertility in patients admitting with a scrotal mass.

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1. Toman’s tuberculosis case detection, treatment, and monitoring- question and answers. In: Frieden T, Deun A (eds). What is the Role of Mycobacterial Culture in Diagnosis and Case Definition? WHO/HTM/TB/2004.334. p.35-43.
2. Pablo-Mendez A. How many drug-resistant tubercule bacilli can be found in the sputum of patients who have never receieved treatment for tuberculosis? In: Frieden T (ed). Toman’s Tuberculosis Case Detection, Treatment, and Monitoring-Question and Answers WHO/HTM/TB/2004; 334: 203-6.
3. Espinal M, Frieden T. What are the causes of: drug-resistant tuberculosis? In: Frieden T (ed). Toman’s Tuberculosis Case Detection, Treatment, and Monitoring-Question and Answers WHO/HTM/TB/2004; 334: 207-8.
4. Republic of Turkey Ministry of Health Department of Tuberculosis Tuberculosis Turkey War, The 2010 Report.
5. Anti-tuberculosis drug resistance in the world. Fourth global report. The WHO/IUATLD global project on anti-tuberculosis drug resistance surveillance, 2002-2007. Geneva, World Health Organization, 2008 (WHO/HTM/TB/2008.394)
6. TB/HIV A Clinical Manual; WHO/HTM/TB/2004; 329: 104.
7. Luna Caminero AJ. Tuberculosis Guide for Specialist Physicians. 2003 IUATLD 68 boulevard Saint Michel, 75006 Paris- France. 2003: 308-48.
8. http://64.233.169.104/search?q=cache:DcowjvFd_ e4J:www.cdc.gov/tb/surv/surv2005/PDF/table27.pdf+table+ 27.+Extrapulmonary+tuberculosis&hl=tr&ct=clnk&cd= 1&gl=tr
9. Iseaman MD. A Clinician’s guide to tuberculosis extrapulmonary tuberculosis. In: Pine WJ, Millet CK (eds). Extrapulmonary Tuberculosis in Adults. 2002: 145-97.
10. Hsieh HC, Lu PL, Chen YH, Chen TC, Tsai JJ, Chang K, et al. Genitourinary tuberculosis in a medical center in southern Taiwan: an eleven-year experience. J Microbiol Immunol Infect 2006; 39: 408-13.
11. García-Rodríguez JA, García Sánchez JE, Muñoz Bellido JL, Montes Martínez I, Rodríguez Hernández J, Fernández Gorostarzu J, et al. Genitourinary tuberculosis in Spain: review of 81 cases. Clin Infect Dis 1994; 18: 557-61.
12. Christensen WI. Genitourinary tuberculosis: review of 102 cases. Medicine (Baltimore) 1974; 53: 377-90.
13. Viswaroop BS, Kekre N, Gopalakrishnan G. Isolated tuberculous epididymitis: a review of forty cases. J Postgrad Med 2005; 51: 109-11.
14. Viswaroop B, Johnson P, Kurian S, Chacko N, Kekre N, Gopalakrishnan G. Fine-needle aspiration cytology versus open biopsy for evaluation of chronic epididymal lesions: a prospective study. Scand J Urol Nephrol 2005; 39: 219-21.