Güngör ÇAMSARI, Dilek YILMAZBAYHAN, Aygün GÜR, Dilek KANMAZ, Gülcihan ÖZKAN, Nur Dilek BAKAN

Churg-Strauss sendromu (iki olgu nedeniyle)

Churg-Strauss sendromu, astım, periferik kanda eozinofili, eozinofilik doku infiltrasyonu ve ekstravasküler granülomlarla karakterize, birçok organı tutan nekrotizan bir vaskülittir. Otuzbeş yaşında, altı aydır astım tanısı olan bir erkek hasta ve 43 yaşında, dört yıldır astım tanısı olan bir kadın hasta klinik bozulma ve akciğer grafilerinde lezyonlar görülmesi nedeniyleileri tetkik edildi. Yapılan incelemeler sonucunda Churg-Strauss sendromu tanısı konuldu. Oral kortikosteroid tedavi ile klinik ve radyolojik yanıt alındı.

Churg-Strauss syndrome (two case reports)

Churg-Strauss syndrome is a necrotizing vasculitis with multiple organ involvement characterized by asthma, peripheral blood eosinophilia, eosinophilic tissue infiltration and extra vascular granulomas. A 35 years-old male with 6-months history of asthma and a 43 years-old female with 4-years history of asthma, were further examined due to clinical worseningand lesions on chest radiographs. They were finally diagnosed as Churg-Strauss syndrome. Clinical and radiological response to oral corticosteroid therapy was obtained.

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