SERPİL EROL, Mehmet PARLAK

Short-term treatment and sustained virologic response in two chronic hepatitis C cases

Kronik hepatit C infeksiyonunda standart tedavi genotip 1 ile enfekte hastalarda pegile interferon-alfa (Peg-IFN-α) ve ribavirin kombinasyonunun 48 hafta uygulanmasıdır. Genotip 2 ve 3 enfeksiyonlarında 24 haftalık konvansiyonel interferon ve ribavirin kombinasyonu ya da ribavirinle birlikte veya tek başına uygulanan Peg-IFN-α tedavisi önerilmektedir. Biz burada antiviral tedavinin önerilen süreden daha erken sonlandırılmasına rağmen kalıcı viral yanıt elde edilmiş, genotipi bilinmeyen iki kronik hepatit C olgusunu sunduk.

Kronik hepatit C enfeksiyonlu iki olguda kısa süreli tedavi ve kalıcı virolojik yanıt

The standard treatment for chronic hepatitis C infection is the combination of pegylated interferon-alpha (Peg-IFN-α) and ribavirin for 48 weeks in patients infected with genotype-1. In genotype-2 or -3 infections, treatment by either conventional IFN-α and ribavirin or Peg-IFN-α with or without ribavirin for 24 weeks is recommended. We hereby report two cases of chronic hepatitis C infection whose genotypes are not specified, with sustained virological response despite early discontinuation of antiviral treatment.

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