Subakut granülomatöz tiroidit ve papiller mikrokarsinom birlikteliği
Çoğunlukla viral bir enfeksiyon sonrası görülen ve kendiliğinden iyileşebilen subakut tiroidit enflamatuvar bir tiroid hastalığıdır. Subakut tiroiditin papiller karsinom ile birlikteliği oldukça nadirdir. Boğaz ağrısı ve boyunda şişlik yakınmaları ile başvuran 58 yaşındaki erkek hastaya fizik muayene, ultrasonografi ve laboratuvar incelemesinden sonra total tiroidektomi yapıldı. Histopatolojik incelemede her iki lobda çok sayıda granülom yapısı izlendi ve sol lobda 2 mm çapında papiller mikrokarsinom odağı görüldü. Subakut tiroidit ve papiller karsinom birlikteliği oldukça nadir görüldüğünden sunulmaya değer bulundu
Co-occurrence of subacute granulomatous thyroiditis and papillary microcarcinoma
Subacute thyroiditis, which is most commonly observed after a viral infection and may heal spontaneously, is an inflammatory thyroid disease. The co-occurrence of subacute thyroiditis and papillary carcinoma is quite rare. A 58-year-old male patient who applied to our hospital with the complaints of sore throat and neck swelling was performed total thyroidectomy following physical examination, ultrasound, and laboratory analysis. In histopathological examination, many granuloma structures were observed in both lobes, and a papillary microcarcinoma focus of 2 mm in diameter was seen in the left lobe. The co-occurrence of subacute thyroiditis and papillary carcinoma was deemed worthy of presentation as it is rarely observed.
___
- Benbassat CA, Olchovsky D, Tsvetov G, Shimon I. Subacute thyroiditis: clinical characteristics and treatment outcome in fifty-six consecutive patients diagnosed between 1999 and 2005. J Endocrinol Invest 2007;30:631-5.
- Choi YS, Kim BK, Kwon HJ, Lee JS, Heo JJ, Jung SB, et al. Subacute thyroiditis with coexisting papillary carcinoma diagnosed by immediately repeat fine needle aspiration: a case report. J Med Cases 2012;3:308-11.
- Ucan B, Delibasi T, Cakal E, Arslan MS, Bozkurt NC, Demirci T, et al. Papillary thyroid cancer case masked by subacute thyroiditis. Arq Bras Endocrinol Metabol 2014;58:851-4.
- Zacharia TT, Perumpallichira JJ, Sindhwani V, Chavhan G. Gray-scale and color Doppler sonographic findings in a case of subacute granulomatous thyroiditis mimicking thyroid carcinoma. J Clin Ultrasound 2002;30:442-4.
- Fatourechi V, Aniszewski JP, Fatourechi GZ, Atkinson EJ, Jacobsen SJ. Clinical features and outcome of subacute thyroiditis in an incidence cohort: Olmsted County, Minnesota, study. J Clin Endocrinol Metab 2003;88:2100-5.
- Azer P, Zhai J, Yu R. Atypical de Quervain’s thyroiditis masquerading as papillary thyroid cancer. Endocrinol Nutr 2013;60:158-9.
- Adair CF. Non-neoplastic lesion of the thyroid gland. In: Thompson LD ,editor. Head and Neck Pathology. 2nd ed. Philadelphia: Elsevier; 2013. p. 508-12.
- Jhaveri K, Shroff MM, Fatterpekar GM, Som PM. CT and MR imaging findings associated with subacute thyroiditis. AJNR Am J Neuroradiol 2003;24:143-6.