M. Zafer UĞUZ, Haydar Kazım ÖNAL, Özlem ÖZGER EROĞLU, Demet ETİT

Parotis kitlelerinde ince iğne aspirasyon biyopsisinin duyarlılık ve özgüllüğü

Amaç: Parotiste kitle saptanan hastalarda ince iğneaspirasyon biyopsisinin İİAB tanısal duyarlılık veözgüllüğü değerlendirildi.Hastalar ve Yöntemler: Çalışmaya parotiste kitlenedeniyle İİAB ve parotidektomi uygulanan 29 hastaalındı. Tüm hastalarda ayrıntılı öykü alındıktansonra, kulak burun boğaz ve sistemik muayeneleryapıldı. Boyun ultrasonografisi ve gerektiğinde boyun bilgisayarlı tomografisinden yararlanıldı. Ameliyat öncesinde tüm hastalara İİAB yapıldı. Yirmi hastaya yüzeyel, dokuz hastaya total parotidektomi uygulandı. Bulgular: İnce iğne aspirasyon biyopsisi sonuçları 21hastada %72.4 benign, altı hastada %20.7 malign,iki hastada %6.9 kuşkulu olarak bildirildi. Ameliyatsonrası patoloji sonuçları 17 hastada %58.6 benign,12 hastada %41.4 malign idi. Parotis kitlelerinin değerlendirilmesinde İİAB’nin duyarlılığı %54.6, özgüllüğü %100 bulundu. Ameliyat sonrası patoloji sonuçlarına göre en sık rastlanan tümörler pleomorfik adenom n=7, %24.1 , mukoepidermoid karsinom n=4, %13.8 ve Warthin tümörü n=3, %10.3 idi.Sonuç: Parotis kitlelelerinde ameliyat öncesi İİAB yapılması cerrahi planlamada önemli bir role sahiptir

Anahtar Kelimeler:

İğne biyopsisi, parotis neoplazileri/patoloji, duyarlılık ve özgüllük

Sensitivity and specificity of fine needle aspiration biopsy in parotid masses

Objectives: We aimed to determine the sensitivity and specificity of fine needle aspiration biopsy FNAB in patients with parotid masses.Patients and Methods: The study included 29patients 15 males, 14 females; mean age 52 years; range 20 to 83 years who underwent FNAB and parotidectomy for parotid masses. After a detailed history taking, otorhinolaryngologic and systemic examinations were performed. Neck ultrasonogra- phy and, when needed, neck computed tomography were used. Superficial parotidectomy was per formed in 20 patients and total parotidectomy in nine patients.Results: The results of FNAB were reported as benign in 21 patients 72.4% , malignant in six patients 20.7% , and suspicious in two patients 6.9% . Postoperative histopathologic diagnoses were reported as benign in 17 patients 58.6% and malignant in 12 patients 41.4% .The sensitivity and specificity rates for FNAB were 54.6% and 100%, respectively. The most common histopathological diagnosis was pleomorphic adenoma n=7, 24.1% , followed by mucoepidermoid carcinoma n=4,13.8% , and VVarthin’s tumor n=3, 10.3% .Conclusion: Preoperative FNAB for parotid masses plays an important role in planning surgery.

Keywords:

Biopsy needle, parotid neoplasms/pathology, sensitivity and specificity,

PDF

___

Gete Garcia P, Almodovar Alvarez C, Garcia Alvarez G, Rodriguez Francos MI, Cervan Rubiales F, Sango Lamban P. Parotid tumours: correlation between fine needle aspiration biopsy and histological findings. Acta Otorrinolaringol Esp 2006; 57:279-82. [Abstract]
Nerheim OO, Freng A, Sauer T. Fine needle aspiration of tumors of the salivary glands. Tidsskr Nor Laegeforen 1997;117:4074-6. [Abstract]
Suen JY, Synderman NL. Benign neoplasms of the sali- vary glands. In: Cummings CW, Fredrickson JM, Harker LA, Krause CJ, Schuller DE, editors. Otolaryngology- head and neck surgery. 2nd ed. St. Louis: Mosby-Year Book: 1993. p. 1029-42.
Hoşal N, Turan E, Ceryan K, Kaya S, Ayas K, Gürsel B, ve ark. Tükürük bezi tümörleri. Türk ORL Arşivi, 1987;25:61-5.
Pinkston JA, Cole P. Incidence rates of salivary gland tumors: results from a population-based study. Otolaryngol Head Neck Surg 1999;120:834-40.
Eisele DW, Johns ME. Salivary gland neoplasms. In: Bailey BJ, editor. Head and neck surgery-otolaryngol- ogy. 2nd ed. Philadelphia: Lippincott-Raven; 1998. p. 1485-508.
Das DK, Petkar MA, Al-Mane NM, Sheikh ZA, Mallik MK, Anim JT. Role of fine needle aspiration cytology in the diagnosis of swellings in the salivary gland regions: a study of 712 cases. Med Princ Pract 2004; 13:95-106.
Gnepp DR, Schroeder W, Heffner D. Synchronous tumors arising in a single major salivary gland. Cancer 1989;63:1219-24.
Uğuz MZ, Hamdioğlu Y, Toprak S, Gökbulut S. Parotis tümörü. İzmir Devlet Hastanesi Mecmuası 1985;23:367.
Cuhruk Ç, Yılmaz O. Parotis bezi kitlelerinde tanı yön- temleri. Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi 1993;1:155-98.
Eneroth CM, Franzen S, Zajicek J. Aspiration biopsy of salivary gland tumors. A critical review of 910 biop- sies. Acta Cytol 1967;11:470-2.
Eneroth CM, Franzen S, Zajicek J. Cytologic diagnosis on aspirate from 1000 salivary-gland tumours. Acta Otolaryngol Suppl 1967;224:168-72.
Lukas J, Duskova J. Fine-needle aspiration biopsy in the diagnostic of the tumors and non-neoplastic lesions of salivary glands. Bratisl Lek Listy 2006; 107:12-5.
Gluckman J, Gullane P, Johnson J. Tükrük bezleri, baş- boyun tümörlerine yaklaşım. Çeviri editörleri: Cevan- şir B, Kıyak E. İstanbul: Nobel Tıp Kitabevleri; 1995. s. 17-32.
Que Hee CG, Perry CF. Fine-needle aspiration cytol- ogy of parotid tumours: is it useful? ANZ J Surg 2001; 71:345-8.
daLilly-Tariah OB, Nwana EJ, Mohammed AZ. Cavernous lymphangioma of adult parotid gland in a non-Caucasian female. J Otolaryngol 2000;29:190-1.
Cohen MB, Reznicek MJ, Miller TR. Fine-needle aspi- ration biopsy of the salivary glands. Pathol Annu 1992; 27 Pt 2:213-45.
Bottles K, Miller TR, Cohen MB, Ljung BM. Fine nee- dle aspiration biopsy. Has its time come? Am J Med 1986;81:525-31.
Rodriguez HP, Silver CE, Moisa II, Chacho MS. Fine- needle aspiration of parotid tumors. Am J Surg 1989; 158:342-4.
Zurrida S, Alasio L, Tradati N, Bartoli C, Chiesa F, Pilotti S. Fine-needle aspiration of parotid masses. Cancer 1993;72:2306-11.
Jayaram G, Dashini M. Evaluation of fine needle aspi- ration cytology of salivary glands: an analysis of 141 cases. Malays J Pathol 2001;23:93-100.