Nanoselüloz İçeren Polimetil Metakrilat Kemik Çimentoları: Üretim Prosesinin ve Silanizasyonun Mekanik Özelliklere Etkisi

Amaç: Kemik çimentosu, kalça implantlarını sabitlemek için klinik uygulamalarda gerekli ortopedik malzemelerden biridir. Bununla birlikte, kemik çimentosu kullanımı, implantasyon bölgesi ile mekanik uyumsuzluk gibi bazı sınırlamalara tabidir. Bu sınırlamaların üstesinden gelmek için bazı dolgu maddelerinin ve kemik çimentosu formülasyonlarının kullanılmasına rağmen, daha iyi çözümlere hala ihtiyaç vardır. Nanoselülozun (NC), doğal, kristal ve güçlü yapısı sayesinde kemik çimentoları ile formülasyon oluşturmada başarılı sonuçlar vermesi mümkündür. Materyal-Metot: Bu çalışmada, değişik yöntemlerle üretilen NC içeren kemik çimentolarının mekanik performansı ve kemik çimentosundaki değişken oranları incelenmiştir. Ayrıca, silanizasyon yöntemiyle karşılaştırmalı bir çalışma ile kompozit teknolojide fazlar arası uyumluluğun arttırılması için kullanılan ve aynı oranların silanize edilmiş ve silanize edilmemiş NC partiküllerin kemik çimentosu formülasyonlarında kullanılması araştırılmıştır. Bulgular: BC-1SNC dışındaki tüm numunelerin sıkıştırma testlerinde şekil deformasyonu öncesi yüklenen maksimum kuvvetler (Fmax), anlamlı derecede farklı değildir (p>0,05). BC- 1SNC, Fmax’ı %12,6 artıran sıkıştırma direncini iyileştirmiştir (p

Nanocellulose Containing Polymethyl Methacrylate Bone Cements: Effect of Production Process and Silanization on Mechanical Characteristics

Objective: Bone cement is one of the essential orthopedicmaterials in clinical applications for fixing hip implants.However, the use of bone cement is subject to some limitationslike mechanical mismatch with the implantation site. Despitethe use of some fillers and bone cement formulations to tacklethese limitations, there is still a need for better solutions. It ispossible for nanocellulose (NC) to yield successful results increating a formulation with bone cements thanks to its natural,crystal and strong structure.Material-Method: In this study, the mechanical performanceof bone cements containing NC that is produced with varyingmethods, and varying ratios in bone cement was examined.Moreover, a comparative study by the silanization method; whichis used for enhancing the inter-phase compatibility in compositetechnology; and employing the same ratios in NC formulationswith silanized and non-silanized particles was conducted.Results: The maximum forces (Fmax) loading before shapedeformation in compression tests of all samples except BC-1SNC were not significantly different (p>0.05). BC-1SNCimproved the compression resistance increasing the Fmax by12.6% (p

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