THE INVESTIGATION THERMODYNAMICAL PROPERTIES OF CARNOSIC ACID AND CARNASOL IN ROSEMARY (ROSMARINUSOFFICINALIS) BY USING HF (HARTRE-FOCK) AS THEORETICAL

THE INVESTIGATION THERMODYNAMICAL PROPERTIES OF CARNOSIC ACID AND CARNASOL IN ROSEMARY (ROSMARINUSOFFICINALIS) BY USING HF (HARTRE-FOCK) AS THEORETICAL

The antioxidants effects of Carnasol and Carnosic acid from Rosemary are calculated as theoretical by using HF;The result of the calculation obtained,Carnosic acid is more satable and eager to give reaction then carnasol.

___

[1] Frankel, E.N.,Huang S., Aeschbach, R.and Prior, E., 1996, Antioxidant Activity of a Rosemary Extract and Its Constituents, Carnosic Acid, Carnosol, and Rosmarinic Acid, in Bulk Oil and Oil-in-Water Emulsion, J. Agric. Food Chem.,44, 131-135.

[2] Richheimer, S.L., Bernart, M.W., King, G.A., Kent, M.C., Bailey, D.T., 1996, Antioxidantactivity of lipid-soluble phenolic diterpenes from rosemary. Journal AOCS. 73:507-514.

[3] 2000 biberiye.com – powered by webhavuzu a.s. http://www.biberiye.com/tanim.htm[accessed August 17,2015].

[4] Akgül, A., Ayar, A. 1993. Yerli baharatların antioksidan etkileri. Doğa-TR. J. of Agriculture and Forestry. 17:1061-1068. 5. Serdaroğlu M, Felekoğlu E. 2005. Effects of using rosemary extract and onion juice on oxidative stability of sardine (Sardina pilchardus) mince. J. Food Quality 28, 109–120.

[6] Yanishlieva, N. V., Marinova, E., Pokorny, J., Natural antioxidants from herbs and spices. Eur. J. Lipid Sci. Technol. 2006, 108, 776–793.

[7] Kırıcı, S. ve İnan, M., 2002, Effect of Different Harvesting Time on the Essential Oil Content of Rosemary (Rosmarinusofficinalis L.) in the Çukurova Conditions. In Proceedings of the Workshop on Agricultural and Quality Aspects of Medicinal and Aromatic Plants.

[8] Lopez-Jimenez,A.,Garcıa-Caballero,M., Medina,M.A., Quesada,A.R., 2013, Anti-angiogenic properties of carnosol and carnosic acid, two majör dietary compounds from rosemary, Eur. J. Nutr., 52:85–95.

[9] Theoduloz, C., Pertino, M.W. andSchmeda-Hirschmann, G., 2014,Gastroprotective Mechanisms of Action of SemisyntheticCarnosicAcidDerivatives in Human Cells, Molecules, 19, 581-594.

[10] Park, S.Y., Song, H., Sung, M.K., Young-Hee, K., Won, K., Han, L.J., Park, Y., 2014, Carnosic Acid Inhibits the Epithelial-Mesen chymal Transitionin B16F10 Melanoma Cells: A Possible Mechanism for the Inhibition of Cell Migration, Int. J. Mol. Sci., 15, 12698-12713.

[11] Chien-chung C., Hui-ling C., Chia-wen H., Yi-ling Y., Being-sun W., 2011, Upregulation of NF-E2-related factor-2-dependent glutathione by carnosol provokes a cytoprotective response and enhances cell survival, Acta Pharmacologica Sinica, 32: 62–69.

[12] Çoban, Ö.E., Patır, B., 2010, Antioksidan Etkili Bazı Bitki ve Baharatların Gıdalarda Kullanımı, Electronic Journal of Food Technologies, 5(2), (7-19).