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Aşırı Doz Siklopentolat Göz Damlasına Bağlı Gelişen Santral Antikolinerjik Sendrom

Siklopentolat hidroklorür %1 damla göz kliniklerinde çok sık kullanılan topikal midriyatik ve sikloplejik bir ilaçtır. Bu olguda sekiz yaşındaki hastaya yanlışlıkla toplamda 16 damla siklopentolat hidroklorür %1 döküldükten sonra gelişen santral antikolinerjik sendrom sunulmuştur. Dizartri, ataksik yürüyüş, görsel halüsinasyon, ağız şapırdatma, dizoryantasyon ve yüzde kızarıklık gelişen hasta, tıbbi gözetim altında tutulmuş ve tüm bulgular 6 saat içinde spontan düzelmiştir. Özellikle uygun dozda kullanılmayan siklopentolat göz damlasına bağlı sistemik yan etkiler gelişebileceği için bu hastalar gözlem altında tutulmalıdır.

Anahtar Kelimeler:

Siklopentolat hidroklorür %1, toksisite, , aşırı doz

Central Anticholinergic Syndrome Induced by Overdose Cyclopentolate Eye Drops

Cyclopentolate hydrochloride %1 is a commonly used drug as a topical mydriatic and cycloplegic agent in ophthalmology clinics. In this report, an eight years old patient was presented who diagnosed as central anticholinergic syndrome after accidental instillation of a total dose of 16 drops cyclopentolate hydrochloride %1. Patient was strickly monitered as for the symptoms of dysarthria, gait ataxia, visual hallucination, mouth sneezing, disorientation and facial redness. All findings were resolved spontaneously within 6 hours. Cyclopentolate eye drops can cause systemic side effects especially if not used at appropriate dose, thus these patients should be observed.

Keywords:

Cyclopentolate hydrochloride %1, toxicity, overdose,

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