Puberte Prekoks ve Obezite İlişkisinin Değerlendirilmesi

Amaç: Benzer yaşam koşullarına rağmen ergenlik zamanlamasındaki belirgin değişiklik, ergenlik başlangıcında çok sayıda faktörün etkili olduğunu gösterir. Ergenlik başlama yaşını genetik ve çevresel faktörler, stres, sosyoekonomik durum, metabolik hız ve vücut yağ oranı gibi birçok faktör etkiler. Son çalışmalar, ergenlik yaşının daha erkene kaydığını göstermiştir. Çocukluk çağı obezitesinin artan prevalansı buna katkı sağladığı varsayılmaktadır. Bu nedenle puberte prekoks nedeni ile takip edilen hastalarda obezite ve fazla ağırlık sıklığını belirlemek, obezite kemik yaşı, boy yaşı ilişkisini değerlendirmek ve obezite ile hormon profili ilişkisini incelemek amacıyla bu çalışmayı planladık. Araçlar ve Yöntem: Sakarya Eğitim ve Araştırma Hastanesi Çocuk Endokrinoloji polikliniğinde Ekim 2018 ile Ekim 2021 tarihleri arasında takip edilen idiopatik puberte prekoks tanılı 206 hastanın dosyaları retrospektif olarak tarandı. Hastaların dosyalarından antropometrik verileri (yaş, cins, boy, kilo, vücut kitle indeksi, puberte evresi), kemik yaşı, boy yaşı, kilo yaşı kaydedildi. Hastalar vücut kitle indeksine (VKİ) göre normal kilolu, fazla ağırlıklı ve obez olarak gruplandırıldı. Bulgular: Hastaların %97.6’sı (201 hasta) kız, %2.4’ü (5 hasta) erkekti. Hastaların 131’i (%63.6) normal kiloda, 40’ı (%19.4) fazla ağırlıklı, 35’i (%17) obezdi. Gruplar arasında (normal kilo, fazla ağırlıklı ve obez), kilo yaşı, VKİ persentili, boy yaşı, kemik yaşı ve kemik yaşı standart deviasyon skoru (SDS) değerleri arasında anlamlı fark saptandı (sırasıyla p=

Anahtar Kelimeler:

obezite, puberte prekosk, erken puberte, çocuk

Evaluation of the Association between Precocious Puberty and Obesity

Objective: The marked variation in the timing of puberty despite similar living conditions shows that many factors are effective in determining the onset of puberty. Many factors, such as genetic and environmental factors, stress, socioeconomic status, metabolic rate, and body fat ratio, affect the age of puberty onset. Recent studies have shown that the age of puberty onset has shifted to earlier ages. The increasing prevalence of childhood obesity is deemed to contribute this change. Therefore, we planned the present study to determine the rates of obesity and overweight, to evaluate the association between obesity, bone age, and height age, and to examine the association between obesity and hormone profile. Materials and Methods: The medical records of 206 patients diagnosed with idiopathic precocious puberty who were being followed up at the Pediatric Endocrinology outpatient clinic of Sakarya Training and Research Hospital between October 2018 and October 2021 were retrospectively reviewed. Anthropometric data (age, gender, height, weight, body mass index, and puberty stage), bone age, height age, and weight age of the patients were recorded from the medical records. Patients were grouped as normal weight, overweight, and obese by body mass index (BMI). Results: Of the included patients, 97.6% (201 patients) were female and 2.4% (5 patients) were male. One hundred and thirty-one patients (63.6%) had normal weight, 40 (19.4%) were overweight and 35 (17%) had obesity. Significant differences were found between the groups (normal weight, overweight and obese) in terms of weight age, BMI percentile, height age, bone age, and bone age standard deviation score (SDS) (p =

Keywords:

Obesity, precocious puberty, early puberty, child,

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