Çocukluk Çağında Karaciğer Hemanjiyomu Tanısıyla Takip Edilen Hastaların Tiroit Fonksiyon Testlerinin Değerlendirilmesi

Amaç: Bu çalışmanın amacı hemanjiyom tanısı alan hastalarda tiroit fonksiyon testlerinin değerlendirilmesidir. Gereç ve Yöntemler: Ekim 2010-Ekim 2022 yılları arasında hemanjiyom tanısı ile takibe alınan ve tanı anında tiroit fonksiyon testleri bakılmış olan 20 hastanın dosyaları retrospektif olarak incelendi. Hastaların demografik ve klinik özellikleri ile görüntüleme ve laboratuvar bilgileri not edildi. Bulgular: Çalışmaya dahil edilen 20 hastanın 13’ü (%65’i) kız ve 7’si (%35’i) erkekti. Hastaların yaşı 4 gün ile 16,5 yıl arasında değişiyordu (ortanca, 20 ay). 10 hasta (%50) infanttı. 3 hasta (%15) preterm iken, 17 hasta (%85) termdi. Karaciğer hemanjiyomu 17 hastada tesadüfen bulunurken (%85), 2 hastada (%10) karın ağrısı ve 1 hastada (%5) ise antenatal tanı ile saptanmıştı. Karaciğerdeki hemanjiyom boyutları 4 ile 50 mm arasında değişiyordu (ortanca 10 mm). Hastaların tiroit fonksiyonları incelendiğinde 19 hastada (%95) tiroit fonksiyonları normal iken 1 hastada (%5) subklinik hipotiroidi olduğu saptandı. Sonuç: İnfantil hepatik hemanjiyoma bağlı hipotiroidizm için çalışmalar yetersiz olup hangi tip infantil hepatik hemanjiyomda hipotiroidinin görülme riskinin arttığı tam olarak belirlenene kadar takipte hipotiroidi gelişebileceği akılda tutulmalıdır.

Anahtar Kelimeler:

Çocukluk çağı, hemanjiyom, hipotiroidi

Evaluation of Thyroid Function Tests in Patients Followed Up with the Diagnosis of Liver Hemangioma in Childhood

Objective: The aim of this study is to evaluate the thyroid function tests in patients diagnosed with hemangioma. Materials and Methods: Between October 2010 - October 2022 ; the files of 20 patients who were followed up with the diagnosis of hemangioma and whose thyroid function tests were also checked at the time of diagnosis were retrospectively analyzed. Patients demographic and clinical characteristics, imagings and laboratory results were noted. Results: Of the 20 patients included in the study; 13 (65%) were female and 7 (35%) were male. The age of the patients ranged from 4 days to 16.5 years (median, 20 months). 10 patients (50%) were infants. While 3 patients (15%) were preterm, 17 patients (85%) were term. Liver hemangioma was found incidentally in 17 patients (85%); 2 patient (10%) diagnosed with abdominal pain and antenatal diagnosis in 1 patient (5%). Hemangiomas in the liver ranged in size from 4 to 50 mm (median 10 mm). When the thyroid functions of the patients were examined; thyroid functions were normal in 19 patients (95%), and subclinical hypothyroidism was found in 1 patient (5%). Conclusion: Studies for hypothyroidism due to infantile hepatic hemangioma are insufficient, but it should be kept in mind that hypothyroidism may develop in the follow-up until it is fully determined which type of infantile hepatic hemangioma has an increased risk of hypothyroidism.

Keywords:

Childhood, hemangioma, hypothyroidism,

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