El dorsalinin nötrofilik dermatozu

Sweet Sendromu ateş, ağrılı inflamatuvar papül ve nodüllerden oluşan, nötrofilik lökositoz ve histopatolojisinde dermiste yoğun nötrofil infiltrasyonu ile karakterize bir dermatozdur. Sweet sendromunun el dorsumlarının nötrofilik dermatozu (EDND) adı verilen genellikle el dorsumuna lokalize bir formu da vardır. Bu dermatozda lezyonlar, çoğunlukla el dorsumunda yer alırken, palmar yerleşimli olan vaka bildirileri sınırlıdır. Burada nadir görülmesinden dolayı palmar yerleşimli 42 ve 61 yaşlarında iki bayan EDND olgusunu sunuyoruz.

Neutrophilic dermatosis of the dorsal hands

Sweet ‘s Syndrome is characterized by fever, tender inflammatory papules and nodules, that show dense infiltrates by neutrophil granulocytes in the dermis on histologic examination. Sweet Syndrome that is localized in the dorsum of the hands is also known as neutrophilic dermatosis of the dorsal hand (NDDH). Although the lesions are generally present on the dorsum of the hands, few cases have been reported with palmar involvement in the literature. Due to the rarity of palmar involvement dermatosis, two women aged 42 and 61 years with PDND are presented in this article.

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  • 1. Bilgili SG, Karadag AS, Çalka O, Bayram I. Sweet Sendromu: 31 Hastanın klinik ve laboratuvar bulgularının değerlendirilmesi. Turkderm 2013;47:33- 38.
  • 2. Odom RB, James WD, Berger TG. Andrews Diseases of The Skin. 9th ed, Philadelphia: WB Saunders, 2000:155-157.
  • 3. Hönigsmann H, Cohen RP, Wolff K. Inflammatory and Neoplastic Disorders of the Dermis In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, Fitzpatrick TB (Editors). Fitzpatrick’s Dermatology in General Medicine. 5th ed, New York: Mc Graw Hill, 1999:1117-1123.
  • 4. Abbas O, Kibbi AG, Rubeiz N. Sweet’s Syndrome: retrospective study of clinical and histologic features of 44 cases from a tertiary care center. Int J Dermatol 2010;49:1244-1249.
  • 5. Giasuddin AS, El-Orfi AH, Ziu MM, El Barnawi NY. Sweet’s Syndrome: is the pathogenesis mediated by helper T cell type 1 cytokines. J Am Acad Dermatol 1998;39:940-943.
  • 6. Cook E, Epstein R, Miller R. A rare case of idiopathic neutrophilic dermatosis of the hands. Dermatology Online J 2011;17:11.
  • 7. Cohen PR, Kurzock R. Sweet Syndrome: A neutrophilic dermatosis classically associated with acute onset and fever. Clin Dermatol 2000;18:265-282.
  • 8. Cohen PR. Sweet’s Syndrome a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis 2007;2:34.
  • 9. Von Den Driesch P. Sweet’s Syndrome (acute febrile neutrophilic dermatosis). J Am Acad Dermatol 1994;31:535-556.
  • 10. Larsen HK, Danielsen AG, Krustrup D, Weismann K. Neutrophilic dermatosis of the dorsal hands. J Eur Acad Dermatol Venereol 2005;19:634-637.
Pamukkale Tıp Dergisi-Cover
  • ISSN: 1309-9833
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2008
  • Yayıncı: Prof.Dr.Eylem Değirmenci