Yasemin KARAL, Serap Tevhide KARASALİHOĞLU, Nilda TURGUT, Cevat Naci ÖNER, Filiz TÜTÜNCÜLER

Tip 1 Diabetes Mellituslu Çocuklarda Uyarılmış Potansiyellerin Eş Zamanlı Kan Şekeri, Serum ve Hu cre İ çi Magnezyum Du zeyleri ve Glikozillenmiş Hemoglobin ile İ lişkisi

Tip I Diabetes Mellitus çocukluk çağının ciddi komplikasyonlar ile seyreden kronik metabolik hastalıklarından biridir. Bu çalışmanın amacı Tip I Diabetes Mellituslu çocuklarda erken dönemde santral sinir sistemi tutulumunun uyarılmış potansiyeller aracılığıyla değerlendirilmesi ve metabolik değişikliklerle ilişkisini saptamaktır. Çalışmaya 5-14 yaş arasında 31 Tip I Diabetes Mellituslu ve aynı yaş ve cinsiyette 35 sağlam çocuk alındı. Olgulardan 8 saat açlık sonrası HbA1c, kan şekeri, serum ve hücre içi magnezyum düzeyleri için kan örnekleri alındı. Tüm olguların otoskopik muayeneleri, işitme testleri ve uyarılmış potansiyel ölçümleri yapıldı. Gruplar metabolik parametreler, diabet süresi ve uyarılmış potansiyeller açısından karşılaştırıldı. Çalışma grubunun HbA1c ve kan şekeri değerleri kontrol grubuna göre anlamlı düzeyde yüksek, serum Mg değerleri istatistiksel olarak anlamlı oranda düşük saptandı (p

Evoked Potentials in Type 1 Diabetic Children and Their Relation With Synchronous Blood Glucose, Serum and İ ntracellular Magnesium and Glycosylated Haemoglobin Levels

Type I Diabetes Mellitus is a chronic disease associated with high morbidity and complications. The aim of this study was to evaluate central nervous system involvement by evoked potentials in diabetic children and identify the relation with metabolic disturbances. The study comprised of 31 Type I diabetic children with aged 5-14 years and 35 age and sex matched controls. Visual, brainstem auditory and somatosensory evoked potentials, otoacoustic emissions were recorded in all subjects. Metabolic control was evaluated in terms of glyceamia, glycosylated haemoglobin, serum and intracellular magnesium status. Groups were compared due to metabolic processes, disease duration and evoked potentials. In the diabetic group, serum glucose and HbA1c levels were higher and serum magnesium levels were lower (p

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