Otizmde Spektrum Bozukluklarında uygunsuz cinsel davranışlar ve Mirtazapin tedavisi: Bir Olgu Sunumu
Otizm spektrum bozukluğu, yaşamın ilk yıllarında ortaya çıkan sosyal, iletişimsel ve bilişsel becerilerin gelişiminde gecikme ve sapma ile karakterize bir bozukluktur. OSB'deki davranışsal problemler için birçok yaklaşım araştırılmış olmasına rağmen, uygunsuz cinsel davranışların (UCD) tedavisine ilişkin araştırmalar hala çok nadirdir. Mirtazapin, son zamanlarda davranışsal müdahalelerle azalmayan UCD için umut verici bir müdahale olmuştur. Bu yazıda, uygunsuz cinsel davranışları olan 14 yaşındaki otistik bir çocukta mirtazapinin dramatik faydasını sunmayı amaçladık.
Inappropriate sexual behaviors and Mirtazapine treatment in Autism Spectrum Disorders: A case report
Autism spectrum disorder is characterized by patterns of delay and deviance in the development of social, communicative, and cognitive skills that arise in the first years of life. Although many approaches were investigated for the behavioral problems in ASD, investigations of the treatment of inappropriate sexual behaviors (ISB) were still so rare. Mirtazapine has been a promising intervention for the ISB which do not decrease with behavioral interventions recently. In this case, we aimed to present the dramatic benefit of mirtazapine in a 14-year-old autistic boy with inappropriate sexual behaviors.
___
- Lord C, Elsabbagh M, Baird G, Veenstra-Vanderweele J. Autism spectrum disorder. The Lancet. 2018.
- Bennett AE, Miller JS, Stollon N, Prasad R, Blum NJ. Autism Spectrum Disorder and Transition-Aged Youth. Current psychiatry reports. 2018; 20(11): 103.
- DeFilippis M, Wagner KD. Treatment of autism spectrum disorder in children and adolescents. Psychopharmacology bulletin. 2016; 46(2): 18.
- Coskun M, Mukaddes NM. Mirtazapine treatment in a subject with autistic disorder and fetishism. Journal of child and adolescent psychopharmacology. 2008; 18(2): 206-9.
- Realmuto GM, Ruble LA. Sexual behaviors in autism: problems of definition and management. Journal of autism and developmental disorders. 1999; 29(2): 121-7.
- Jones MC, Okere K. Treatment of hypersexual behavior with oral estrogen in an autistic male. Southern medical journal. 2008; 101(9): 959-60.
- Nguyen M, Murphy T. Mirtazapine for excessive masturbation in an adolescent with autism. Journal of the American Academy of Child & Adolescent Psychiatry. 2001; 40(8): 868-9.
- Albertini G, Polito E, Sarà M, Di Gennaro G, Onorati P. Compulsive masturbation in infantile autism treated by mirtazapine. Pediatric neurology. 2006; 34(5): 417-8.
- Coskun M, Karakoc S, Kircelli F, Mukaddes NM. Effectiveness of mirtazapine in the treatment of inappropriate sexual behaviors in individuals with autistic disorder. Journal of child and adolescent psychopharmacology. 2009; 19(2): 203-6.
- Deepmala, Agrawal M. Use of propranolol for hypersexual behavior in an adolescent with autism. Annals of Pharmacotherapy. 2014; 48(10): 1385-8.
- Chen F, Grandjean C, Richard S. Pharmacological management of inappropriate sexual behaviors in youth with autism spectrum disorder: A case study and review of the literature. Neuropsychiatrie de l’Enfance et de l’Adolescence. 2016; 64(3): 163-7.
- Ayaydın H, Ulgar ŞB. Diagnosis and treatment of early childhood masturbation in a case of autism spectrum disorder: a case report. 2018.
- Hergüner S. Otistik bozuklugu olan çocuk ve ergenlerde asiri masturbasyon davranisi: Üç olguda essitalopram etkinligi/Excessive masturbation in children and adolescents with autistic disorder: efficacy of escitalopram in three cases. Anadolu Psikiyatri Dergisi. 2009; 10: S102.
- Dincer M, Gul A, Gul H, Aydın MS, Bodur S, Tas Torun Y, Congologlu MA, Ozmenler KN. Mirtazapine-related manic/hypomanic shift: mini review and case report. Neurological Sciences. 2018; 31: 209-14.