Sevil KARABAĞ, Ayşegül İSAL ARSLAN, Tolga ERSÖZLÜ

Baş-Boyun Skuamöz Hücreli Karsinomlarında EGFR, P16 ve Ki67 Ekspresyonunun Prognoza Etkisi

Amaç: EGFR ve HPV pozitif baş-boyun kanserlerinin, negatif olanlara kıyasla oldukça farklı klinik ve demografik özelliklerinden dolayı HPV ve EGFR ekspresyon durumu bağımsız prognostik faktör olarak kullanılabilir. Bu çalışmanın amacı baş-boyun skuamöz hücreli karsinom vakalarında EGFR, p16 ve ki67 ekspresyonlarının yaşam süresi ile ilişkisini saptamaktır.

Anahtar Kelimeler:

baş&boyun skuamöz hücreli karsinom, EGFR, p16, ki67, prognoz

The Effect of EGFR, P16 and Ki67 Expression on Prognosis in Head and Neck Squamous Cell Carcinoma

Objective: HPV and EGFR expression status may be utilized as an independent prognostic factor owing to the different clinical and demographic characteristics head and neck cancers. In the study, it was aimed to investigate the association between EGFR, p16 and ki67 expression and survival in patients with head and neck squamous cell carcinoma (SCC).

Keywords:

head and neck squamous cell carcinoma, EGFR, p16, Ki67, prognosis,

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