Murat DANACI, Hüseyin AKAN, Ümit BELET, Lütfi İNCESU, Murat BAŞTEMİR, Mustafa Bekir SELÇUK

Soliter pulmoner nodüllerin malign-benign ayrımında dinamik kontrastlı BT incelemesi

Akciğerde soliter pulmoner nodüllerin malign-benign ayrımı pek çok tanı yöntemine rağmen güçtür. Bu çalışmanın amacı dinamik kontrastlı bilgisayarlı tomografi incelemesinin akciğer nodüllerinin malign-benign ayrımındaki katkısını araştırmaktır. Akciğerde nodül saptanan 49 (33 malign, 16 benign) hastaya tek seviyeli dinamik kontrastlı bilgisayarlı tomografi incelemesi yapıldı. Kontrast madde öncesi ve sonrası en yüksek kontrastlanma değerleri arasındaki fark kontrastlanma değeri olarak hesaplandı. Malign ve benign nodüllerde kontrastlanma değerlerinin ortalamaları arasında ilişki varlığı araştırıldı. Malign ve benign nodüllerin kontrastlanma değerlerinin ortalamaları arasında istatistiksel olarak ileri derecede anlamlı fark saptandı (p

Anahtar Kelimeler:

Coin lezyon, pulmoner, Tanı, ayırıcı, Tanı teknikleri, solunum sistemi, Tanısal görüntüleme, Akciğer neoplazmları, Duyarlılık ve özgüllük, Tomografi, x-ışınlı bilgisayarlı

Dynamic contrast enhanced computed tomography in malign-benign differentiation of solitary pulmonary nodules

The aim of this study is to evaluate the contribution of dynamic contrast enhanced computed tomography to malign-benign differentiation of solitary pulmonary nodules. Dynamic contrast enhanced computed tomography obtained at a single level was performed in 49 patients (33 malign, 16 benign) with pulmonary nodules. The difference between the highest contrast enhancement values before and after contrast material injection was calculated as the enhancement value. The correlation between mean enhancement values of malignant and benign nodules was evaluated. Statistically significant difference was found between the mean enhancement values of malign and benign nodules (p<0.001). When the enhancement value over 20 Hounsfield Unite is accepted as the border for malignancy, the sensitivity and specificity of the method were 90% and 91%, respectively. We suggest that dynamic contrast enhanced computed tomography can be useful in management of patients by supplying very important additional informations in malign-.benign differention of pulmonary nodules.

Keywords:

Coin Lesion, Pulmonary, Diagnosis, Differential, Diagnostic Techniques, Respiratory System, Diagnostic Imaging, Lung Neoplasms, Sensitivity and Specificity, Tomography, X-Ray Computed,

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