May Ursodeoxycholic Acid Significantly Improve Liver Function Tests among Patients with Hepatitis C?

In their relevant study, the authors demonstrated that ursodeoxycholic acid therapy significantly improvedliver function tests either when given alone or combined with silymarin. But, silymarin itself failed to improve liver function tests. We thank to the authors for their valuable contribution. However, there are some concerns that need to be explained in a detailed manner for a better understanding of the results presented in the manuscript.

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El Menshawe SF, Ahmed AS, Abdelaty LN, Aty LNA, Abo Seif MA. Study of hepatoprotective effect of silymarin and ursodeoxycholic acid in chronic Hepatitis C Patients. Med-Science. 2014;3(4):1655-74.

2. Coppola A, DiCapua M, Conca P. Noninvasive assessment of liver fibrosis in patients with chronic hepatitis C (and congenital bleeding disorders): where do westand? Semin Thromb Hemost. 2013;39(7):803-15.

3. Konerman MA, Yapali S, Lok AS. Systematic review: identifying patients with chronic hepatitis C in need of early treatment and intensive monitoring-predictors and predictive models of disease progression Aliment Pharmacol Ther. 2014;40(8):863-79.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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