Butane Gas Inhalation Resulting in Death: Two Case Reports

Today, abuse of volatile substances is an increasingly common public health problem in Turkey, as throughout the world. These substances are attractive to childen and adolescents as products containing inhalants are relatively inexpensive, legally and easily accessible, have a rapid effect and unwanted symptoms disappear quickly. Case No 1: A 16-year old male collapsed in the street who was intubated by paramedics and taken to the Emergency Department. A cigarette lighter and gas refill can were found in his pockets. Case No 2: The dead body of a 17-year old male who lived with his parents was found in the kitchen of their house. There was a court record of substance abuse inhalation. In the autopsies of both cases, the brain and cerebellum were observed to be hyperemic and oedematous. Hyperemia was also observed in tracheal and gastric mucosa. Toxicological and histopathological analyses were applied after the autopsies. Butane, as the active ingredient of lighter gas, was confirmed in samples of blood, bile and internal organs in the toxicology analysis. Histopathological examination of the brain, cerebellum, lung, liver and kidneys determined congestion. In this study, it was aimed to emphasize the importance of the causes of the increasing prevalence of inhalant abuse in children and young adults and the significance of forensic autopsy in the determination of the cause of death. To prevent inhalant abuse of substances which can be obtained cheaply and easily in our country, visual-auditory education-training and appropriate legal regulations are required.

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1. Uzun N, Karaali Savrun F, Kızıltan ME. Kronik toluen ve n-heksan intoksikasyonunda periferik sinir sistemi hasari: elektrofizyolojik inceleme. Cerrahpaşa Tıp Fakültesi Dergisi. 2001;32(3):142-50.

2. Altındağ A, Özkan M, Oto R. İnhalanla ilişkili bozukluklar. Klinik Psikofarmakoloji Bülteni. 2001;11:143-8.

3. Yaşan A, Gürgen F. Güneydoğu Anadolu bölgesinde ergenlerde uçucu madde kullanim özellikleri. Bağımlılık Dergisi. 2004;5(2):28-34.

4. Kurtzman TL, Kimberly NO, Richard AW. Inhalant abuse by adolescents. Journal of Adolescent Health. 2001;28(3):70-80.

5. Crowley TJ. Inhalant Related Disorders. In: Comprehensive Textbook of Psychiatry, HI Kaplan ve BJ Sadock (Ed), 6. Ed., Baltimore, Williams Wilkins, 1995:838-42.

6. Kaya B, Özcan ME. Uçucu bağımlılığı ve kötüye kullanımı: Epidemiyoloji, risk grupları ve önleme programlarının gerekliliği. Klinik Psikiyatri. 1999;2:189-96. 7. Kumar S, Grover S, Kulhara P, Mattoo SK, Basu D, Biswas P, Shah R. Inhalant abuse:

A clinic-based study. Indian J Psychiatry. 2008;50(2):117-20.

8. Dilbaz N. Uçucuların kullanimina bağli ruhsal ve davranişsal bozukluklar. In: T.C.Sağlık Bakanlığı Sağlık Hizmetleri Genel Müdürlüğü Madde Bağımlılığı Tanı Ve Tedavi Kılavuzu El Kitabı. Ankara, 2012:157.

9. Ives R. Disorders relating to the use of volatile substance. In: Gelder MG, Lopez Ibor JJ, Andreasen NC, eds, New Oxford Textbook of Psychiatry. New York: Oxford University Press, 2000;546-50.

10. Cohen S. Inhalant abuse: an overview of the problem. NIDA Res Monogr. 1977;15:2- 11.

11. Akcan R, Çekin N, Hilal A, Arslan MM. Gençlerde uçucu madde soluma sonucu ani ölüm: Olgu sunumu. Dicle Tıp Dergisi. 2010;2:154-6.

12. Anderson CE, Loomis GA. Recognition and prevention of inhalant abuse. Am Fam Physician. 2003;68(5):869-74.

13. Sugie H, Sasaki C,Hashimoto C, Takeshita H, Nagai T, Nakamura S, Furukawa M, Nishikawa T, Kurihara K. Three cases of sudden death due to butane or propane gas inhalation: analysis of tissues for gas components. Forensic Sci Int. 2004;143(2- 3):211-4.

14. Evren C, Öğel K, Tamar D, Çakmak D. Uçucu madde kullanıcılarının özellikleri. Bağımlılık Dergisi. 2001;2(2):57-60.

15. Flanagan RJ, Ruprah M, Meredith TJ, Ramsey JD. An introduction to the clinical toxicology of volatile substances. Drug Safety. 1990;5(5):359-83.

16. Pfeiffer H, Al Khaddam M, Brinkmann B, Köhler H, Beike J. Sudden death after isobutane sniffing: A report of two forensic cases. Int J Legal Med. 2006;120(3):168- 73.

17. Pyatt JR, Gilmore I, Mullins PA. Abnormal liver function tests following inadvertent inhalation of volatile hydrocarbons. Postgrad Med J. 1998;74(878):747-8.

18. H. Naitou, Chudoku Hyakka, 2nd edition, Nanzando, Tokyo, 2001:164-6.

19. Gross A, Klys M. Suicide by propane-butane inhalation. A case report and literature review. Arch Med Sadowej Kryminol. 2002;52(1):37-42.

20. Bass M. Sudden sniffing death. JAMA. 1970;212(12):2075-9.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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