Isolated coronary artery bypass surgery in patients with mild to moderate ischemic mitral regurgitation: Early results

The optimal management of moderate ischemic mitral regurgitation (MR) remains controversial. Some surgeons advocate coronary artery bypass alone, while others suggest concomitant mitral valve annuloplasty. We aimed to evaluate the early results of isolated coronary artery bypass operation on the cases with mild-to-moderate ischemic MR. Between May 2010 and May 2011, 59 patients (64% male, mean age: 50.5 years) with a preoperative diagnosis of mild-to-moderate ischemic MR underwent a coronary bypass operation. Patients evaluated with preoperative and postoperative (in twelve-month period with an average of five months) transthoracic echocardiogram (TTE). Postoperative mortality was not observed in study group. The preoperative functional capacity of the patients as well as the variables of mild MR and moderate MR showed a statistically significant difference in a positive way when compared with the postoperative functional capacity and MR variables. Postoperative TTE evaluation revealed that only 2 cases have severe MR (3,4%) also 62,7 % of patients have mild and 33.9% of patients have moderate MR. While there was a significant difference in a positive way between the preoperative and postoperative period in terms of left atrial diameter, no significant difference was found for the variables of ejection fraction and pulmonary artery pressure. Among the patients whom undergoing coronary bypass surgery, if there is mild or moderate MR revealed with the TTE prior to the operation, performing only coronary bypass operation will be adequate, and our early results in this matter are satisfactory. But, if severe MR revealed with TTE, performance of mitral valve repair or replacement should be evaluated additional to coronary bypass operation.

___

Aklog L, Filsoufi F, Flores KQ, Chen RH, Cohn LH, Nathan NS,Byrne JG, Adamas DH. Does coronary artery bypass grafting alone correct moderate ischemic mitral regurgitation? Circulation. 2001;104:I-68-I-75.

Izhar U, Daly RC, Dearani JA, Orszulak TA, Schaff HV, Mullany CJ. Mitral Valve Replacement or Repair After Previous Coronary Artery Bypass Grafting. Circulation. 1999;100:II-84-Ii-89.

Sade LE. Fonksiyonel mitral yetersizliği. Anadolu Kardiyol Derg. 2009;9:3-9.

Perez de Isla L, Zamorano J, Quezada M, Almeria C, Rodrigo JL, Serra V, Garcia Rubira JC, Ortiz AF, Macaya C. Prognostic significance of functional mitral regurgitation after a first non-ST-segment elevation acute coronary syndrome. Eur Heart J. 2006;27(22):2655-60.

Lehmann KG, Francis CK, Dodge HT. Mitral regurgitation in early myocardial infarction: incidence, clinical detection, and prognostic implications. TIMI Study Group Ann Intern Med. 1992;117(1):10-7.

Yetim M, Karaagac K, Sasmaz A, Yılmaz M. The Relationship Between Left Atrial Mechanical Function and Functional Capacity in Mitral Stenosis. J Clin Anal Med. 2013;4(6):458-61.

Otsuji Y, Handschumacher MD, Schwammenthal E, Jiang L, Song J-K, Guerrero JL, Vlahakes GJ, Levine RA. Insights from three-dimensional echocardiography into the mechanism of functional mitral regurgitation direct in vivo demonstration of altered leaflet tethering geometry. Circulation. 1997;96(6):1999-2008.

Gopal AS, King DL, Katz J, Boxt LM, King DL Jr, Shao MY. Threedimensional echocardiographic volume computation by polyhedral surface reconstruction: in vitro validation and comparison to magnetic resonance imaging. J Am Soc Echocardiogr. 1992;5(2):115-24.

Di Mauro M, Di Giammarco G, Vitolla G, Contini M, Iacò AL, Bivona A, Weltert L, Calafiore AM. Impact of no-to-moderate mitral regurgitation on late results after isolated coronary artery bypass grafting in patients with ischemic cardiomyopathy. Ann Thorac Surg. 2006;81(6):2128-34.

DeRose Jr JJ, Toumpoulis IK, Balaram SK, Ioannidis JP, Belsley S, Ashton Jr RC,Swistel DG, Anagnostopoulos CE. Preoperative prediction of longterm survival after coronary artery bypass grafting in patients with low left ventricular ejection fraction. J Thorac Cardiovasc Surg. 2005;129(2):314-21.

Czer L, Maurer G, Bolger AF, DeRobertis M, Chaux A, Matloff JM. Revascularization alone or combined with suture annuloplasty for ischemic mitral regurgitation. Evaluation by color Doppler echocardiography. Tex Heart Inst J. 1996;23(4):270-8.

Tolis GA, Korkolis DP, Kopf GS, Elefteriades JA. Revascularization alone (without mitral valve repair) suffices in patients with advanced ischemic cardiomyopathy and mild-to-moderate mitral regurgitation. Ann Thorac Surg. 2002;74(5):1476-81.

Kim Y-H, Czer LS, Soukiasian HJ, De Robertis M, Magliato KE, Blanche C, Raissi SS, Mirocha J, Siegel RJ, Kass RM, Trento A. Ischemic mitral regurgitation: revascularization alone versus revascularization and mitral valve repair. Ann Thorac Surg. 2005;79(6):1895-901.

Ogus NT, Us MH, Ogus H, Isik O. Coronary artery bypass grafting alone for advanced ischemic left ventricular dysfunction with significant mitral regurgitation: early and midterm outcomes in a small series. Tex Heart Inst J. 2004;31(2):143-8.

Prifti E, Bonacchi M, Frati G, Giunti G, Leacche M, Proietti P, Babatasi G, Sani G. Should Mild‐to‐Moderate and Moderate Ischemic Mitral Regurgitation Be Corrected in Patients with Impaired Left Ventricular Function Undergoing Simultaneous Coronary Revascularization? J Card Surg. 2001;16(6):473-83.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
Sayıdaki Diğer Makaleler

A new heart surgery clinic: Open Heart Surgery Outcomes at Karabük Training and Research Hospital: Assessment of the first year

Emre KUBAT, Celal Selcuk UNAL, Aydin KESKİN, Emre GÖK, Ufuk Turan Kürşat KORKMAZ, Ümit KERVAN, Mustafa PAÇ, Kasım KARAPINAR

Investigation of the microorganisms decaying blood evidences

Murat OGDUR, Hüseyin ÇAKAN, FİLİZ EKİM ÇEVİK

Did we overcome rheumatic heart disease or is it still a public disease burden?

Erkan YILDIRIM, Barış BUĞAN

Effects of enteral and total parenteral nutrition on length of stay in intensive care unit in postoperative period

MUSTAFA SAİD AYDOĞAN, RAMAZAN PAŞAHAN, Ali KARADEMİR, AYTAÇ YÜCEL, Buğra KARAKAŞ, Türkan TOĞAL

General anesthesia management in 15 preterm infant undergoing diode laser photocoagulation for retinopathy of prematurity: a retrospective study

AHMET SELİM ÖZKAN, Sedat AKBAŞ, NİHAT POLAT

Correlation between red cell distribution width and grade of hepatic steatosis and liver enzymes in patients with Non-Alcoholic steatohepatitis

ALİ DOĞAN, Narin YILDIRIM DOĞAN, ÖMER EKİNCİ, Melih KARINCAOĞLU

Retrospective investigation of the effectiveness of fecal occult blood test (FOB), PT-APTT in patients admitted to emergency department with gastrointestinal bleeding

Ekim SAĞLAM GÜRMEN, Mücahit AVCİL, Bekir DAĞLI, KIVANÇ KARAMAN

Opinions of nurses working in NICU about family centered care

DİLEK KÜÇÜK ALEMDAR, FUNDA KARDAŞ ÖZDEMİR, SEVİNÇ POLAT

Bone mass and bone turnover in premenopausal women with fibromyalgia syndrome

Ali GÜRBÜZ, ARZU KAYA, TANSEL ANSAL BALCI

Assessment of job satisfaction and quality of life in public health assistants

Burak METE, Erkay NACAR, Yusuf LEVENT, Esin CAKMAK, ÇİĞDEM TEKİN, ALİ ÖZER