Colorectal cancers are the third most common tumors both in the world and in Turkey. Its frequency may vary according to geographical regions, environmental conditions and feeding habits. This study aimed to investigate the distribution of CRC patients admitted to Mardin State Hospital Medical Oncology Outpatient Clinic according to age, sex, diagnosis and stage. The records of patients admitted to Mardin State Hospital Medical Oncology Clinic between 2014-2018 were reviewed retrospectively. Patients over 18 years of age were included in the study. Gender, diagnosis and disease stages of the patients were recorded. A total of 1208 patients were examined. 160 colorectal cancer patients (13.2%) were detected. 74 (46.3%) of the patients were female and 86 (53.8%) were male. The male / female patient ratio was 1.16 / 1. While the median age of the whole group was 57 (19-93), the median age of the women was 57.78 (24-86) and the median age of the men was 56 (19-93). The ratio of colon cancer / rectal cancer in men was 54/32 (62.8 / 37.2%), whereas it was 44/30 (59.5 / 40.5%) in women. There was no difference in the age of the groups according to the diagnosis of colon and rectal cancer and gender (p = 0.37 and p = 0.59). There was no difference between the groups when the diagnoses and stages were compared by gender (p = 0.66 and p= 0.18). When the application stage was examined in all groups, the least application was in stage 1, and the most common application was in stage 4. 32 patients (20%) were over 70 years old and 19 (11.9%) were over 75 years old. The number of patients ≤49 years and 50-64 years were 51 (31.9%) and 64 (40%), respectively. This study includes the first CRC data of Mardin province. CRC patients in Mardin are diagnosed at a younger age and in an advanced stage. Since diagnosis and treatment methods are not sufficient in Mardin, patients are mostly diagnosed outside the province. Therefore, the number of patients is limited. Nevertheless, the statistics will be the first to guide future studies.
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1. Jemal A, Clegg LX, Ward E, et al. Annual report to the nation on the status of cancer, 1975–2001, with a special feature regarding survival. Cancer: Interdisciplinary Int J Am Cancer Society. 2004;101:3-27.
2. American CS. Cancer Facts and Figures 2011. Atlanta. 2011.
3. Fund WCR, Research AIfC. Food, nutrition, physical activity, and the prevention of cancer: a global perspective: Amer Inst for Cancer Research; 2007.
4. Gültekin M, Boztaş G. Türkiye kanser istatistikleri. Sağlık Bakanlığı, Türkiye Halk Sağlığı Kurumu. 2014;43.
5. Ferlay J, Soerjomataram I, Ervik M, et al. Cancer incidence and mortality worldwide: IARC CancerBase. GLOBOCAN 2012 v10. 2012;11.
6. Haggar FA, Boushey RP. Colorectal cancer epidemiology: incidence, mortality, survival, and risk factors. Clin Colon Rectal Surg. 2009;22:191-7.
7. Edwards BK, Howe HL, Ries LA, et al. Annual report to the nation on the status of cancer, 1973–1999, featuring implications of age and aging on US cancer burden. Cancer. 2002;94:2766-92.
8. Boyle P, Leon ME. Epidemiology of colorectal cancer. British Medical Bulletin. 2002;64:1-25.
9. Siegel R, DeSantis C, Jemal A. Colorectal cancer statistics, 2014. CA: A Cancer J For Clin. 2014;64:104-17.
10. Murphy G, Devesa SS, Cross AJ, et al. Sex disparities in colorectal cancer incidence by anatomic subsite, race and age. Int J Cancer. 2011;128:1668-75.
11. Meissner HI, Breen N, Klabunde CN, et al. Patterns of colorectal cancer screening uptake among men and women in the United States. Cancer Epidemiology and Prevention Biomarkers. 2006;15:389-94.
12. Yalçın BM, Turan E, Yücel İ, ve ark. İlk kez tanı konan kolorektal kanser hastalarının epidemiyolojik özellikleri. Türkiye Aile Hekimliği Dergisi. 2012;16:169-77.
13. Gürsoy Ş, Özlem E, Canöz Ö, ve ark. Kayseri ve yöresinde kolon kanserlerinin özellikleri. Akademik Gastroenteroloji Dergisi. 2003;2.
14. Özgören E, Kisli E, Aydın M, ve ark. Kolorektal kanserlerde tedavi yaklaşımlarımız. Van Tıp Dergisi. 2001;8:124-7.
15. Labianca R, Beretta GD, Kildani B, et al. Colon cancer. Critical Reviews In Oncology/Hematology. 2010;74:106-33.
16. Sundermeyer ML, Meropol NJ, Rogatko A, et al. Changing patterns of bone and brain metastases in patients with colorectal cancer. Clin Colorectal Cancer. 2005;5:108-13.
17. Health NIo. Surveillance, epidemiology, and end results (SEER) program SEER* stat database: incidence-SEER 9 regs research data, Nov 2016 Sub (1973-2014). National Cancer Institute, D, Surveillance Research Program. 2017.
18. Siegel RL, Miller KD, Fedewa SA, et al. Colorectal cancer statistics, 2017. CA: A Cancer J For Clin. 2017;67:177-93.
19. Howlader N. Noone AM, editor;, Krapcho M, editor., et al. eds. SEER Cancer Statistics Review, 1975–2013. Bethesda, MD: National Cancer Institute; 2016. 2017.
20. Howlader N. Noone aM, Krapcho M, et al (eds). sEER Cancer statistics Review, 1975-2010, National Cancer Institute. Bethesda, MD. 2013.