Effect of different positive end-expiratory pressures in donor liver transplantation patients on hemodynamics and ICU admission period: A Prospective, randomized, double-blind study

Donors are generally volunteers without any sanitary problems. For this reason, security of the anesthesia practice and ICU admission period is significant. The goal of present study was to determine whether there was any important coalition among different positive end-expiratory pressure (PEEP) level hemodynamics and ICU admission in donor patients. This study was performed with40 patients who underwent general anesthesia. Patients were divided into two groups by their PEEP as0 cm H20 in the first group (group Z), and 10 H20 in the second group (group H). We investigated the data concerning demographical data, perioperative values, hemodynamic parameters, intraoperative blood loss, andICU admission. Patient characteristic,characteristicsand perioperative values were similar among the groups. Mean arterial pressure, and central venous pressure were importantly different among the groups (P.05). We have concluded that our data pool is low and single-centered,we determined that PEEP values (10 cm H2O) may be a decisive element for the ICU admission after donor patients.

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Ayanoglu HO, Ulukaya S, Yüzer Y, et al. Anesthetic management and complications in living donor hepatectomy. Transplant Proc. 2003;35:2970.

Saner FH, Pavlakovic G, Gu Y, et al. Does PEEP impair the hepatic outflow in patients following liver transplantation? Intensive Care Med. 2006;32:1584.

Saner FH, Damink SWM, Pavlakovic G, et al. Positive endexpiratory pressure induces liver congestion in living donor Liver transplant patients: myth or fact. Transplantation. 2008;85:1863

Hess DR, Thompson BT. Ventilatory strategies in patients with sepsis and respiratory failure. Curr Infect Dis Rep. 2005;7:342.

Saner FH, Pavlakovic G, Gu Y, et al. Effects of positive endexpiratory pressure on systemic haemodynamics, with special interest to central venous and common iliac venous pressure in Liver transplanted patients. Eur J Anaesthesiol. 2006;23:766.

Sand L, Rizell M, Houltz E, et al. Effect of patient position and PEEP on hepatic, portal and central venous pressures during liver resection. Acta Anaesthesiol Scand. 2011;55:1106.

Saner FH, Damink SWM, Pavlakovic G, et al. How far can we go with positive end-expiratory pressure (PEEP) in liver transplant patients? J Clin Anesthes. 2010;22:104.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: Yılda 4 Sayı
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
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