Coexistence of PFAPA syndrome with separation anxiety

PFAPA syndrome is an auto inflammatory disease. Researchers have stated that auto inflammatory mechanisms can play a role in etiology of several psychiatric diseases and for this reason auto inflammatory diseases are frequently associated with psychiatric disorders. The purpose of this paper, it is aimed to report two cases diagnosed with PFAPA syndrome and having psychiatric symptoms and to discuss them accompanied by literature data. As authors, in the light of cases we report and literature knowledge, we think that children with PFAPA syndrome could be under risk in terms of psychiatric problems due to common inflammatory etiology.

___

Thomas KT, Feder HM, Lawton AR, et al. Periodic fever syndrome in children. J Pediatr. 1999;135:15-21.

Brown KL, Wekell P, Osla V, et al. Profile of blood cells and inflammatory mediators in periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. BMC Pediatr. 2010;10:65.

Mitchell RH, Goldstein BI. Inflammation in children and adolescents with neuropsychiatric disorders: a systematic review. J Am Acad Child Adolesc Psychiatry. 2014;53:274-96.

Marshall GS, Edwards KM, Butler J, et al. Syndrome of periodic fever, pharyngitis, and aphthous stomatitis. J Pediatr. 1987;110:43-6.

Vigo G, Zulian F. Periodic fevers with aphthous stomatitis, pharyngitis, and adenitis (PFAPA). Autoimmun Rev. 2012;12:52-5.

Henje BE, Lekander M, Ingvar M, et al. Proinflammatory cytokines are elevated in adolescent females with emotional disorders not treated with SSRIs. J Affect Disord. 2012;136:716-23.
Medicine Science-Cover
  • ISSN: 2147-0634
  • Yayın Aralığı: 4
  • Başlangıç: 2012
  • Yayıncı: Effect Publishing Agency ( EPA )
Sayıdaki Diğer Makaleler

The risks and benefits of non-predictive splenectomy: The necessity of splenectomy and early postoperative outcomes

YUSUF GÜNAY, İLHAN TAŞDÖVEN

Epidemiology of Blastocystis spp. in primary school students at a central village of Ordu province

Ülkü KARAMAN, Zeynep KOLÖREN, Emine AYAZ, Ümit GÜR

Factors affecting selection of anesthesia type in elective cesarean operations and pregnant preferences for anesthesia outcome

Barış ARSLAN, Nilgün KAVRUT ÖZTÜRK, Zinet Asuman ARSLAN ONUK, BİLGE KARSLI

The effect of measurement uncertainty for HOMA-IR in assessment of insulin resistance

MÜJGAN ERCAN KARADAĞ, AYŞEN CANİKLİOĞLU, Esra FIRAT OĞUZ, ÇİĞDEM YÜCEL, Mehmet ÖZCAN, FATMA MERİÇ YILMAZ, SEDAT ABUŞOĞLU, Canan TOPÇUOĞLU, Yusuf BAYRAKÇEKEN

Common Demodex spp. identified on the arm and abdominal region of patient monitored for widespread pruritus

YASEMİN KAYA, SEVDA ÖNDER, Ülkü KARAMAN, Gamze KAÇMAZ

Parenteral systemic antifungal drugs and their clinical drug informations

İREM BOZBEY, Zeynep Ülkü GÜN, ARZU KARAKURT

Amiodarone induced thyrotoxicosis may not respond to therapeutic plasma exchange like patients with graves’ disease: A report of two cases and literature review

İsmail YILDIZ, GÜLŞAH ELBÜKEN, Tugay ATASEVER, SİBEL ÖZKAN GÜRDAL, SAYİD SHAFİ ZUHUR

Synthesis and the effect of a novel benzoxazole compound on breast cancer cell line

FUNDA KOSOVA, Özlem TEMİZ ARPACI, ERCÜMENT ÖLMEZ, MEHMET İBRAHİM TUĞLU

Pancreatic injury due to blunt abdominal trauma in children

BURHAN BEGER, Baran Serdar KIZILYILDIZ, Metin ŞİMŞEK, HÜSEYİN AKDENİZ, Bülent SÖNMEZ

The evaluation of two different surgical approaches in total hip arthroplasty according to the patient satisfaction, plantar pressure distribution and trendelenburg sign

Ahmet YILDIRIM, Tacettin AYANAOĞLU, MUSTAFA ÖZER, Erdinç ESEN, Ulunay KANATLI, Selçuk BÖLÜKBAŞI