Yüksek Nitratlı Diyetle Beslenen Ankara Keçilerinde Tiroid Hormonları Üzerine Kükürt İlavesinin Etkileri
Bu çalışma, yüksek diyetli nitrat alımı ve inorganik kükürt ilavesinin Ankara keçilerindeki tiroid hormonlarına etkisini belirlemek amacıyla yapıldı. Çalışmada, yaklaşık 14 aylık yaştaki 18 erkek Ankara keçisi 3 gruba bölündü: kontrol grup bazal diyetle beslendi, nitrat grubu 1500 ppm nitrat ilave edilen bazal diyetle beslendi ve nitrat+kükürt grubu 1500 ppm nitrat ve %1.8 sodyum sülfat ilave edilen bazal diyetle beslendi. Çalışmanın 45., 90., 135. ve 180. günlerinde serum örneklerinde tiroid uyarıcı hormon (TSH), total ve serbest triiyodotironin (TT3 veFT3) ve tetraiyodotironin (TT4 ve FT4) düzeyleri ölçüldü. 180. günde, TT4 hariç, serum TSH, total ve serbest T3 ve serbest T4 konsantrasyonları nitrat+kükürt grubunda kontrol ve nitrat grubundan daha yüksekti (P<0.01). Bu çalışma, Ankara keçilerinin tiroid hormonları dikkate alındığında 1500 ppm nitrat içeren bir beslemeyi tolere edebileceğini ve inorganik kükürdün doza bağlı olarak tiroid hormonları üzerine yüksek nitratlı diyetin olumsuz etkilerini hafifletmek için doğal bir kaynak görevi görebileceğini önermektedir.
Effects of Sulfur Supplementation on Thyroid Hormones in Angora Goats Fed With a High-Nitrate Diet
This study was to aimed for determination the effect of high dietary nitrate intake and inorganic sulphur supplementation on thyroids hormones in Angora goats. In this study, eighteen male Angora goats aged 14 months were divided into three groups (n = 6): control group fed with a basal diet, nitrate group fed with a basal diet supplemented with 1500 ppm nitrate, and nitrate + sulfur group fed with a basal diet supplemented with 1500 ppm nitrate and 1.8% sodium sulfate. On days 45, 90, 135, and 180 of the study, the concentrations of the thyroid-stimulating hormone (TSH), total and free triiodothyronine (TT3 and FT3), and tetraiodothyronine (TT4 and FT4) were measured in the serum samples. On day 180, except for TT4, the serum TSH and total and free T3 and free T4 concentrations were higher (P<0.05) in the nitrate + sulfur group than in the control and nitrate groups. This study suggested that Angora goats could tolerate a feed containing 1500 ppm nitrate with respect to the thyroid hormones, and inorganic sulfur might serve as a natural source for alleviating the negative effects of the high-nitrate diet on the thyroid gland in a dose-dependent manner.
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