Andaç Hamamcı, Kezban Berberoğlu, Özcan Gündoğdu, Cemile Ceylan, Hande Baş Ayat, Kayıhan Engin

ERKEN EVRE KÜÇÜK HÜCRELİ DIŞI AKCİĞER KANSERLERİNİN TEDAVİSİNDE ROBOTİK RADYOCERRAHİ

Amaç: Bu çalışmada Anadolu Sağlık Merkezi’nde robotik SBRT uygulanan erken evre akciğer kanserli olguların tedavi sonuçları geriye dönük olarak incelenip lokal kontrol ve sağkalım süreleri istatistiksel olarak raporlanmaya çalışıldı. Yöntem: Kliniğimizde 2005-2016 tarihleri arasında SBRT uygulanan opere edilemeyen ya da cerrahi istemeyen, T1-T2N0M0 evre 135 olgunun incelendi. 87 olgu Synchrony Takip yöntemi ile, 34 olgu X Sight Lung yöntemi ile tedavi edilirken 17 olgu X Sight Spine Takip yöntemi ile tedavi edildi. Medyan fraksiyon sayısı 3 (1-8) idi. Medyan BED10 değeri ise 180 Gy (45-180’ di. Tedaviye yanıt BT ve/veya PET/BT ile değerlendirildi. Medyan yaş değeri 65 (44-88) olan olguların 108’i erkek iken 27’si kadındı. Medyan takip süresi 19 (3-88), medyan sağkalım ise 34 ay hesaplandı. Bulgular: Çalışmaya dahil edilen olgulara ait 1, 2, 3 ve 5 yıllık sağkalım %88, %72, %50 ve %39 iken aynı süreler için lokal kontrol ise %81, %54, %51 ve % 39 olarak elde edildi. BED=180 Gy ve BED

ROBOTIC STEREOTACTIC BODY TREATMENT FOR EARLY STAGE NON-SMALL CELL LUNG CANCER

Objective: In this study, we retrospectively reviewed and statistically analyzed the Cyberknife SBRT outcomes in terms of local control and survivaltimes for the patients with primer lung tumors treated at Anadolu Medical Center.Methods: We included 135 patients who were treated between 2005 and 2016 and diagnosed primary lung cancer who were judged medicallyinoperable. median BED10 was 180 Gy (ranging 45-180). The treatment response was assessed using either a CT or a PET-CT scan or both. Therewere 108 men and 27 women, with an overall median age of 65 years (range 44-88 years). The median follow-up and overall survival were 19 (3-88)and 34 months, respectively.Results: Overall survival and local control of the patients for 1, 2, 3, 5 years were 88%, 72%, 50%, 39%, and 81%, 54%, 51%, 39%, respectively. 1,2 and 3 year survival rates for BED10=180Gy group were 89%, 84% and 72% respectively. 1, 2 and 3 year survival rates were found as 88%, 68%and 42% for BED

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