Hüseyin EREN, Mustafa Ozan HORSANALI, Eyüp DİL, Emin ÖZBEK

Visceral Adiposity Index and Overactive Bladder in Postmenopausal Woman: A Novel Predictive Risk Factor

ABSTRACT INTRODUCTION: To investigate the association between visceral adiposity index (VAI) and overactive bladder (OAB) symptoms in postmenopausal female patients aged over 45 years. MATERIALS AND METHODS: Between March 2017 and December 2017, 76 postmenopausal female patient with OAB symptoms were evaluated. Anthropometric indices serum cholesterol levels, fasting glucose levels, urodynamic findings and OAB-8 scores were recorded. VAI was calculated according to gender-specific formula. Participants were divided into three groups according to VAI levels. The relationship between VAI and OAB symptoms were statistically compared in terms of urodynamic outcomes and OAB-8 scores. RESULTS: Mean age of the patients were 57.2 8.3 years and mean BMI was 32.3 2.8 kg/m2. Statistical significance was observed in terms of abdominal pressure (Pabd), post voiding residual urine mounts (PVR), maximum bladder capasity (MBC) and OAB-8 scores between groups. VAI correlated positively with PVR, detrusor overactivity (DOA), urinary frequency, urge incontinence, nocturia and OAB-8 scores whereas a negative correlation existed MBC and first desire to void. CONCLUSIONS: We observed that patients with higher levels of VAI had more OAB symptoms and worse urodynamic findings.VAI may also be used as a marker for predicting overactive bladder symptoms

Postmenozal Kadınlarda Visseral Adipozite İndeksi ve Aşırı Aktif Mesane: Yeni Bir Risk Belirteci

ÖZ AMAÇ: 45 yaş üstü postmenopozal kadın hastalarda visseral adipozite indeksi (VAI) ile aşırı aktif mesane semptomları arasındaki ilişkiyi araştırmak. METARYAL VE METOD: Mart 2017- Aralık 2017 tarihleri arasında aşırı aktif mesane semptomları olan 76 postmenopozal kadın hasta değerlendirildi. Antropometrik veriler, serum kolesterol düzeyleri, açlık glukoz seviyeleri, ürodinamik bulgular ve OAB-8 formu kayıt edildi. VAI cinsiyete özgü formüle göre hesaplandı. Hastalar VAI seviyelerine göre üç gruba ayrıldı. VAI ile aşırı aktif mesane semptomları arasındaki ilişki ürodinamik sonuçlar ve OAB-8 skoru açısından istatiksel olarak karşılaştırıldı. BULGULAR: Hastaların yaş ortalaması 57.2 8.3 yıl, ortalama vücut kitle indeksi (VKİ) 32.3 2.8 kg/ m2 idi. Gruplar arasında Pabd, post miksiyonel rezidü idrar miktarı (PMRİ), maksimum mesane kapasitesi (MMK) ve OAB-8 sorgulama formu skoru açısından anlamlı fark bulundu. VAI ile PMRİ, detrüsor aşırı aktivitesi (DAA), idrar sıklığı, urge inkontinans, noktüri ve OAB-8 skoru arasında pozitif korelasyon, MMK ve ilk işeme arzusu açısından negatif korelasyon tesbit edildi. SONUÇ: VAI düzeyi yüksek olan hastalarda daha fazla aşırı aktif mesane semptomu olduğunu ve daha kötü ürodinamik bulguları olduğunu gözlemledik. VAI ayrıca aşırı aktif mesane semptomlarını öngörmede bir belirteç olarak kullanılabilir

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