Premenstrual Dysphoric Disorder and Affective Temperament in Patients with Polycystic Ovary Syndrome

INTRODUCTION: This study aimed to evaluate the affective temperaments of women with Polycystic Ovary Syndrome (PCOS), to assess its comorbidity with Premenstrual Dysphoric Disorder (PMDD) and compare with Healthy Controls (HC). METHODS: A total of 20 women with PCOS and 20 HC were included in this study. Hospital Anxiety and Depression Scale (HADS) and Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionnaire version (TEMPS-A) were applied to all participants. The Diagnoses of PMDD and other psychiatric disorders were made by staff psychiatrists interviewing all participants using DSM-5 diagnostic criteria. RESULTS: The comorbidity of PMDS in patients with PCOS was 30% (n=6), while it was 15% (n=3) in the HC group. PMDS proportions did not differ significantly between groups. Patients with PCOS had higher major depression (25%, n=5) and anxiety disorders (20%, n=4) compared with HCs, but only anxiety disorders were significantly higher in PCOS than the HC group (p=0.03). DISCUSSION and CONCLUSION: Patients with PCOS may have more comorbidity risk of PMDD, which is a mood disorder according to DSM–5, and associated with menstrual cycles. Considering and treating PMDD and other psychiatric conditions may increase the quality of life and functionality of women with PCOS.

Polikistik Over Sendromlu Hastalarda Premenstrüel Disforik Bozukluk ve Affektif Mizaç

GİRİŞ ve AMAÇ: Bu çalışmada, Polikistik Over Sendromu (PKOS) olan kadınların, afektif mizaç özelliklerini ve Premenstrual Disforik Bozukluk (PMDB) komorbiditesini değerlendirmek ve Sağlıklı Kontrollerle (SK) karşılaştırmayı hedefledik. YÖNTEM ve GEREÇLER: Bu çalışmaya 20 PKOS hastası ve 20 SK dahil edildi. Tüm katılımcılara Hastane Anksiyete ve Depresyon Ölçeği (HADÖ) ve Mizaç Karakter Envanteri (Temperament Evaluation of Memphis, Pisa, Paris and San Diego-Autoquestionnaire version (TEMPS-A)) uygulandı. PMDB ve diğer psikiyatrik bozuklukların tanıları, DSM-5 tanı ölçütlerini kullanarak tüm katılımcılarla bire bir görüşen uzman psikiyatristler tarafından yapıldı. BULGULAR: PKOS'lu hastalarda PMDB'nin eştanısı% 30 (n = 6) iken SK grubunda % 15 (n = 3) idi. PMDB oranları bakımından gruplar arasında anlamlı farklılık gözlenmedi. PKOS'lu hastalarda SK'lere göre daha yüksek oranda majör depresyon (% 25, n = 5) ve anksiyete bozukluğu (% 20, n = 4) olmakla birlikte, sadece anksiyete bozuklukları PKOS'da SK grubuna göre anlamlı derecede yüksekti (p = 0.03). TARTIŞMA ve SONUÇ: PKOS'lu hastalar, DSM-5’e göre duygudurum bozuklukları arasında olan ve adet döngüsü ile ilişkili olan PMDB komorbiditesi açısından risk faktörüne sahip olabilirler. PKOS’lu kadınlarda, PMDB ve diğer psikiyatrik durumları düşünmek ve tedavi etmek, bu hastaların yaşam kalitesini ve işlevselliğini artırabilir.

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1. Ehrmann DA. Polycystic ovary syndrome. N Engl J Med 2005;11:1223–36.

2. Li Y, Li Y, Yu Ng EH, Stener-Victorin E, Hou L, Wu T, et al. Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis. Fertil Steril 2011;96: 452–8.

3. Hahn S, Janssen OE, Tan S, Pleger K, Mann K, Schedlowski M, et al. Clinical and psychological correlates of quality-of-life in polycystic ovary syndrome. Eur J Endocrinol 2005;11:853–60.

4. Setji, TL, Brown AJ. Polycystic ovary syndrome: update on diagnosis and treatment. Am J Med 2014;127:912–9.

5. Davari-Tanha F, Hosseini Rashidi B, Ghajarzadeh M, Noorbala AA. Bipolar disorder in women with polycystic ovarian syndrome (PCOS). Acta Med Iran 2014;52(1):46–8.

6. Kerchner A, Lester W, Stuart SP, Dokras A. Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study. Fertil Steril 2009;91(1):207–12.

7. Bhattacharya SM, Jha A. Prevalence and risk of depressive disorder in women with polycystic ovary syndrome (PCOS). Fertil Steril 2010;94:357– 9.

8. Jedel E, Waern M, Gustafson D, Landén M, Eriksson E, Holm G, et al. Anxiety and depression symptoms in women with polycystic ovary syndrome compared with controls matched for body mass index. Hum Reprod 2010;25(2):450-6.

9. Naqvi SH, Moore A, Bevilacqua K, Lathief S, Williams J, Naqvi N, et al. Predictors of depression in women with polycystic ovary syndrome. Arch Womens Ment Health 2015;18:95– 101.

10. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Arlington, VA: American Psychiatric Association; 2013.

11. Nevatte T, O 'Brien PM, Backstrom T, Brown C, Dennerstein L, Endicott J, et al. Is PMD consensus on the management of premenstrual disorders. Arch Women Ment Health 2013;1 6:279 -91.

12. Yonkers KA, O'Brien PM, Eriksson E. Premenstrual syndrome. Lancet 2008;371: 1200 - 1210.

13. Akiskal HS, Akiskal KK, Haykal RF, Manning JS, Connor PD. TEMPS-A: progress towards validation of a self-rated clinical version of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire. J Affect Disord 2005; 85;3 – 16.

14. de Aguiar Ferreira A, Vasconcelos AG, Neves FS, Correa H. Affective temperaments and antidepressant response in the clinical management of mood disorders J Affect Disord 2014; 155:138– 41.

15. Kesebir A, Gundogar D, Kucuksubas Y, Tatlıdil Yaylacı E. The relation between affective temperament and resilience in depression: A controlled study. J Affect Disord 2013; 148:352–6.

16. Park C, An SK, Kim HW, Koh MJ, Namkoong K, Kang JI. Relationships between chronotypes and affective temperaments in healthy young adults. J Affect Disord 2015;175:256–9.

17. Shahini M, Shala M, Xhylani P, Gashi S, Borinca I, Erfurth A. Challenging predictions between affective temperaments, depression and anxiety in a Kosovo student community sample. Int J Psychiatry Clin Pract 2018:26:1-7.

18. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004;19:41–7.

19. Legro RS, Arslanian SA, Ehrmann DA, Hoeger KM, Murad MH, Pasquali R. Diagnosis and treatment of polycystic ovary syndrome: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2013;98:4565–92.

20. Ferriman D, Gallwey JD Clinical assessment of body hair growth in women. J Clin Endocrinol Metab 1961;21:1440–7.

21. Kerchner A, Lester W, Stuart SP, Dokras A. Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study. Fertil Steril 2009;91:207–12.

22. Tan J, Wang QY, Feng GM, Li XY, Huang W. Increased Risk of Psychiatric Disorders in Women with Polycystic Ovary Syndrome in Southwest China. Chin Med J. 2017; 5;130(3):262- 6.

23. Annagür BB, Kerimoglu ÖS, Tazegül A, Gündüz Ş, Gençoglu BB. Psychiatric comorbidity in women with polycystic ovary syndrome. J Obstet Gynaecol Res 2015; 41(8):1229-33.

24. Asik M, Altinbas K, Eroglu M, Karaahmet E, Erbag G, Ertekin HEvaluation of affective temperament and anxiety-depression levels of patients with polycystic ovary syndrome. J Affect Disord 2015 1;185:214-8

25. Khazaie H, Ghadami MR, Khaledi-Paveh B, Chehri A, Nasouri M. Sleep Quality in University Students with Premenstrual Dysphoric Disorder. Shanghai Arch Psychiatry 2016; 28(3):131-3.

26. Rubinow DR, Schmidt PJ. Gonadal steroid regulation of mood: The lessons of premenstrual syndrome. Front Neuroendocrinol 2006; 27 (2):210–6.

27. Freeman EW, Halbreich U, Grubb GS. An overview of four studies of a continuous oral contraceptive (levonorgestrel 90 mcg/ethinyl estradiol 20 mcg) on premenstrual dysphoric disorder and premenstrual syndrome. Contraception 2012;85(5):437-45.

28. Sveindottir H, Backstrom T. Prevalence of menstrual cycle symptom cyclicity and premenstrual dysphoric disorder in a random sample of women using and not using oral contraceptives. Acta Obstet Gynecol Scand 2000;79(5):405-13.

29. Hollinrake E, Abreu A, Maifeld M, Van Voorhis BJ, Dokras A. Increased risk of depressive disorders in women with polycystic ovary syndrome. Fertil Steril 2007;87(6):1369-76.

30. Blay SL, Aguiar JV, Passos IC. Polycystic ovary syndrome and mental disorders: a systematic review and exploratory meta-analysis. Neuropsychiatr Dis Treat 2016;12:2895-903.
Kocaeli Tıp Dergisi-Cover
  • ISSN: 2147-0758
  • Başlangıç: 2012
  • Yayıncı: -
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