Mehmet Cihan YAVAŞ, Mehmet Zülküf AKDAĞ, İbrahim KAPLAN, Mustafa Salih ÇELİK

Investigation of The Effects of Electromagnetic Fields on Serum Paraoxonase (PON1)

INTRODUCTION: The widespread use of electrical devices in the society and being in close contact with these devices cause both anxiety and affect public health. The aim of this study is to investigate whether high voltage induced electromagnetic field exposure on different days affects serum paraoxanase 1 activity of rats. METHODS: The study included 24 adult male wistar albino rats, weighing 320 grams on average. They were randomly grouped into 3 as n: 8. Group 1: Sham-control, Group 2: 26 days High voltage (HV) and Group 3: 52 days HV. The rats in the 26-day and 52-day experimental groups (Groups I, II) received electric and magnetic fields for 8 hours each day. RESULTS: We found a decrease in paraoxonase (PON1) activity in the 26- and 52-day high-voltage exposure group compared to the control group. A statistically significant (p=0.000) change was found between the groups. DISCUSSION AND CONCLUSION: :Our study suggests that the exposure to high voltage line may cause a reduction of paraoxonase 1 activity. We've noticed that short-term exposures, compared to long-term ones, may lead to lower paraoxonase 1 activity. Therefore, our study also points to the importance of further research in this regard.

Serum Paraoksonaz (PON1) Üzerine Elektromanyetik Alanların Etkisinin Araştırılması

GİRİŞ ve AMAÇ: Toplumda elektrikli cihazların yaygın olarak kullanılması ve bu cihazlarla yakın temas halinde olması hem endişeye hem de halk sağlığını etkilemektedir. Bu çalışmanın amacı, farklı günlerde yüksek gerilim kaynaklı elektromanyetik alan maruziyetinin, sıçanların serum paraoksanaz 1 aktivitesini etkileyip etkilemediğini araştırmaktır. YÖNTEM ve GEREÇLER: Bu retrospektif çalışmada, Mart 2008-Nisan 2018 tarihleri arasında İstanbul Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi'nde abdominal duvar endometriozisi tanısı alan hastaların bilgisayar tabanlı tıbbi kayıtları incelendi ve analiz edildi. BULGULAR: Yirmi altı ve elli iki günlük yüksek gerilim maruziyet grubunda paraoksonaz (PON1) aktivitesinde kontrol grubuna göre bir azalma bulduk. Gruplar arasında ise istatistiksel olarak önemli (p

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