Cytomegalovirus Hepatitis in Immunocompetent Patient: One Case Report

Cytomegalovirus (CMV) infections cause rare clinical manifestations in immunocompetent adults, usually with asymptomatic or mild clinical manifestations. CMV in immunocompromised patients can cause various clinical tabulations such as gastrointestinal, cardiovasculer, hepatitis, pneumonitis and neurological systems like meningoencephalitis. In this study, presented a case of CMV hepatitis with immunocompetant, lymphomonocytosis and fever.

İmmunkompetan Hastada Sitomegalovirus Hepatiti: Bir Olgu Sunumu

Sitomegalovirus (CMV) enfeksiyonları immunkompetan erişkinlerde nadir klinik bulgulara sebep olmakta, genellikle asemptomatik ya da hafif seyirli klinik tablolar ile seyretmektedir. CMV immunkompromize hastalarda gastrointestinal, kardiyovasküler, hepatit, pnömoni ve nörolojik sistemde meningoensefalit gibi çeşitli klinik tablolara neden olabilmektedir. Bu çalışmada immunkompetan, lenfomonositozu olan ve ateş yakınması ile başvuran hastada CMV hepatiti olgusu sunulmuştur.

PDF

___

1- Qian J.Y, Bai X. Y, Feng Y. L, Zhu W, J, Yao F, Li J. N, Yang A. M, Li F, Qian J. M. Cholestasis, Ascites and Pancytopenia in an Immunocompetent Adult with Severe Cytomegalovirus Hepatitis. World J Gastroenterol 2015; November 21; 21(43): 12505-12509.

2- Ruiz M. F, Codoceo C. M, Medrano F. L, García R. F, Porras A. C , Castillo C. G et all. Cytomegalovirus Myopericarditis and Hepatitis in an Immunocompetent Adult: Successful Treatmentwith Oral Valganciclovir. Inter Med 47: 1963-1966, 2008.

3- Zubiaurre L, Zapata E, Bujanda L, Castillo M, Oyarzabal I, Stampa M. G, Cosme A. Cytomegalovirus Hepatitis and Myopericarditis. World J Gastroenterol 2007; January 28; 13(4): 647- 648.

4- Gonçalves R, Valente C, Ferreira E, Serra J. E, Cunha J. S. Cytomegalic Hepatitis in a Patient Receiving Omalizumab. IDCases 5 2016; 83–84.

5- Nakasea H, and Herfarthb H. Cytomegalovirus Colitis, Cytomegalovirus Hepatitis and Systemic Cytomegalovirus Infection: Common Features and Differences. Inflamm Intest Dis. 2016 April ; 1(1): 15–23.

6- Koruk S. T, Gürsoy B, Çalışır C, Çelik Y, Tavflan Ö, Ural O. Sağlıklı Erişkinde Ciddi Seyirli CMV Enfeksiyonu. Klimik Dergisi Cilt 20, Say:3 • 2007; S:95-96.

7- Davalos F, Chaucer B, Zafar W, Salman S, Nfonoyim J. Dasatinib-Induced CMV Hepatitisin an Immunocompetent Patient: A Rare Complication of a Common Drug. Translational Oncology 2016; 9, 248–250.

8- Karakoç Z. Ç, Taşçıoğlu D, Tekin S, Şimşek B. Sağlıklı Erişkinde Akut Sitomegalovirus Hastalığı: Dört Olgu Sunumu. Klimik Dergisi 2016; 29(1): 39- 42.

9- Chan A, Bazerbachi F, Hanson B, Alraies M. C, Nelson A. D. Cytomegalovirus Hepatitis and Pancreatitis in the Immunocompetent. The Ochsner Journal 14:295–299, 2014. 10- Güler S, Kökoğlu F. Ö, Uçmak H, Özden S, Kus S, Gül M. Sağlıklı Erişkinde Akut CMV Hepatiti. J Turgut Ozal Med Cent 2013;20(4):354-6.