Astımı Rahatsız Edici ve Riski Azaltıcı Güncel Tedavi

Astım, çoğunlukla çocukluk döneminde ortaya çıkan, alevlenmelere ya da persistan semptomlara neden olan kompleks, kronik inflamatuar bir alt solunum yolu hastalığıdır. Son yıllarda astım tedavisinde “kontrol” kavramı ön plana çıkmıştır, bu kavram ile astımın hem farmakoterapi hem de diğer stratejik önlemlerin alınmasıyla tüm yönleriyle kontrol altına alınması hedeflenmektedir. Astımda farmakoterapi rahatlatıcı tedavi, kontrol edici tedavi ve ağır astımı olan hastalarda ek tedaviler olmak üzere üçe ayrılmaktadır. Kontrol edici astım tedavisi ile havayolundaki inflamasyonun azaltılması, semptomların kontrol altına alınması, gelecek için astım ilişkili atak riskinin ve rahatlatıcı ilaç kullanım oranlarının azaltılması hedeflenir. Günümüzde bir yandan ağır astım tedavisi için çok yönlü araştırılmalar yapılıp yeni ek tedaviler geliştirilirken, diğer yandan intermittan ya da hafif persistan astımı olan hastalar için gerektiğinde ya düzenli olarak kullanılacak farklı tedavi şekillerinin etkinliği ve güvenilirliği araştırılmaktadır. Astım hastalığında patofizyolojideki heterojeniteden dolayı gelecekte herbir basamaktaki tedavi yanıtını belirleyecek diğer klinik, laboratuvar ve genetik belirteçlerin keşfi yol gösterici olacaktır.

Anahtar Kelimeler:

ASTIM, çocuk, tedavi, kontrol, risk

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ISSN: 1309-0453
Başlangıç: 2009
Yayıncı: Selen Medya Yayıncılık Tanıtım ve Organizasyon Hizmetleri

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