Bedriye KOYUNCU SÖKMEN, Soheil SABET

RT-PCR Pozitif COVID-19 Pnömonili Hastalarda Radyolojik Bulguların ve Akciğer Tutulum Oranının Değerlendirilmesi

Amaç: Bu çalışmanın amacı, COVID-19 pnömonisinin görüntüleme özelliklerini ve kantitatif bilgisayarlı tomografi (BT) ile COVID-19’daki pulmoner tutulumun derecesini gözlemlemek ve hastalık yükünü değerlendirmektir. Gereç ve Yöntemler: 20 Mart-20 Nisan 2020 tarihleri arasında retrospektif olarak hastalar çalışmaya dahil edildi. Tüm hastalara real time ters transkripsiyon-polimeraz zincir reaksiyonu (RT-PCR) testi uygulandı. PCR ve BT bulguları pozitif olan 257 hasta (yaş ortalaması 50; yaş aralığı ise 18-91) çalışmaya dahil edildi. Tüm hastaların akciğer bilgisayarlı tomografi bulguları ve tutulum oranları belirlendi. Akciğer hastalığının tutulum oranı ile yaş ve cinsiyet arasındaki ilişkiyi incelemek için nonparametrik istatistiksel testler kullanıldı. Seksen yaş üstü grupta yüksek dansitede akciğer volümü daha yüksek bulundu. Bulgular: SARS-CoV-2 enfeksiyonu olan 257 hasta (147 erkek ve 110 kadın) çalışmaya dâhil edildi. Yüksek dansiteli akciğer volümü erkeklerde kadınlara göre önemli ölçüde daha yüksekti. 40-69 yaş arası hasta grubunda cinsiyetler arasında yüksek yoğunluklu akciğer hacminde anlamlı bir korelasyon gözlendi ve tutulum erkeklerde daha yüksekti. Sonuç: Sonuç olarak çalışmamızda yaş grupları arasında 80 yaş üstü grupta akciğer tutulumu yüzdesinin daha yüksek olduğunu bulduk. Sonuçlarımız, en yüksek riskli hastaların ve özel tedavi stratejilerine ihtiyaç duyanların belirlenmesine yardımcı olabilir.

Anahtar Kelimeler:

Akciğer tutulumu, COVID-19 pnömonisi, Kantitatif Bilgisayarlı Tomografi

Evaluation of Radiologic Findings and Lung Involvement Ratio in RT-PCR Positive Patients with COVID-19 Pneumonia

Objective: The purpose of this study was to observe the imaging characteristics of the COVID-19 pneumonia and extent of pulmonary involvement in COVID-19 with quantitative computed tomography (CT) and to assess of disease burden on. Material and Methods: Patients were retrospectively enrolled in the study from March 20 to April 20, 2020. All patients underwent real-time reverse transcription–polymerase chain reaction (RT-PCR) testing. Two hundred and fifty seven patients (mean age 50 years; range 18-91years) with positive PCR and CT findings were included in the study. Lung computed tomography findings and involvement rates of all patients were determined. Nonparametric statistical tests were used to examine the relationship between the involvement ratio of lung disease and the age or sex. Results: Two hundred and fifty seven patients (147 males and 110 females) with SARS-CoV-2 infection were enrolled. The high density lung volume was significantly higher in males than in females. A significant correlation was observed in high-density lung volume between the genders in the 40-69 age group and the involvement was higher in males. The high density lung percentage was higher in the group above 80 years old. Conclusion: As a result, we found that among the age groups in our study, the percentage of lung involvement was higher in the group above 80 years old. Our results may help to identify the highest-risk patients and those who require specific treatment strategies

Keywords:

COVID-19 pneumonia, Lung involvement, Quantitative computed tomography,

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