Eozinofilik Gastroenterit (EGE) gastrointestinal sistemin infiltrasyonu ile karakterize nadir bir bozukluktur. Eozinofilik asit ise lenfoma, EGE, periton diyalizi ve paraziter enfeksiyonlarla birliktelik gösterebilir. Serozal tip en nadir tip olup, primer seroza hastalığı, eozinofilik asit ve periferik eozinofili ile karakterizedir. Biz burada, tipik tanısal özellikleri ve tedavi cevabı ile birlikte bir  serozal tip EGE vakasını sunduk.On altı yaşında erkek hasta kliniğe karında şişlik ve üç hafta önce başlayıp kendi kendine gerileyen ishal şikâyeti ile başvurdu. Fizik muayenede ortopne, takipne ve belirgin abdominal distansiyon görüldü. Laboratuvar testlerinde belirgin periferal eozinofili ve abdominal sıvıda eozinofil sayısında artış saptandı. Hastaya toplamda altı hafta boyunca steroid tedavisi verildi ve sonuçta gastrointestinal semptomların ve asitin tamamen geçtiği görüldü. Eozinofilik gastroenterit nadir bir bozukluk olmakla birlikte açıklanamayan asit varlığında akılda tutulmalıdır. Eozinofilik gastroenterit, özellikle primer malinitelerde bir dışlama tanısı olmakla birlikte, intestinal infiltrasyona sebep olan birçok sekonder neden de bulunmakta ve tanı için bunların da dışlanması gerekmektedir.

Eosinophilic gastroenteritis (EGE) is a rare disorder and eosinophilic infiltration of the gastrointestinal tract is characteristic for it. Eosinophilic ascites may seen in lymphoma, eosinophilic gastroenteritis, peritoneal dialysis, and parasitic infections too. Depending on the dominant layer of infiltration EGE is classified into three types namely, mucosal, muscularis and serosal. Rarest type is the serosal type characterized by primary serosal disease, peripheral eosinophilia and eosinophilic ascites. Here we report a case of serosal EGE. We have discussed clinical cornerstones for diagnosis and response to treatment.A male patient age of 16 presented to the clinic with complaints of self-limiting diarrhea which stop within three weeks and abdominal distension. In physical examination tachypnea, orthopnea and marked abdominal distension were seen. Contrast-enhanced abdominal computed tomography showed the presence of ascites and diffuse thickening of small bowel wall, but did not detect a primary malignancy in the abdominal cavity; and no signs of portal hypertension or liver disease. In laboratory tests significant eosinophilia in blood and abdominal fluid were seen. Leukocyte count was 16680 /mm3 in the hemogram and 60% eosinophil was detected in the peripheral smear. In paracentesis fluid analysis; eosinophilia (70% eosinophil) were detected. Steroid treatment to be completed in six weeks in total was applied to the patient who was diagnosed with eosinophilic ascites. Therapy with corticosteroids resulted in resolution of both the gastrointestinal symptoms and the ascites without hesitation. He had not any complaint during four months follow-up; ascites regressed and examination was normal. EGE is a rare disorder and it should be flashed in patients who presented with unexplained ascites. Since diagnosis of EGE is a diagnosis of exclusion and, apart from malignancies, there are many other secondary causes of eosinophilic intestinal infiltration that must be excluded.