Ömer DUYURAN, Merve Nur Yenmiş İNAN, Can ACIPAYAM, Ahmet Gökhan GÜLER, Ali Erdal KARAKAYA, Abdulkadir Yasir BAHAR, Nursel YURTTUTAN

Çocukluk Çağında Dev Disgerminomlu Üç Olgu

Disgerminom, dev boyutlara ulaşabilen overin en sık görülen malign tümörüdür. Genelde hormon salgılamamakla beraber beta-HCG salgılayabilirler. Bizde karında kitle ve karın ağrısı şikâyetleri olan radyolojik görüntüleme ile tespit edilen beta-HCG salgılayan dev boyutlara ulaşmış disgerminom tanılı 3 olguyu inceledik. Üç olguya da salpingo-ooferektomi ameliyatı yapıldı. Bir olguda komsu lenf nodlarından, peritondan ve karşı overden örnekleme yapıldı. Bir olgu da üç haftada bir dört kür BEP (Bleomisin, Etoposid, Sisplatin) kemoterapi protokolü ile fertilite de korunarak tedavi sağlanmış oldu. Bir olguda da 3 kür BEP kemoterpi protokülü verilmesi planlandı ve 2 kür BEP kemoterapi protokolü verildi.

Anahtar Kelimeler:

Disgerminom, Çocukluk Çağı

Three Cases of Giant Childhood Dysgerminomas

Disgerminoma is the most common malign tumor of the ovary that can reach giant sizes. In general, although they do not secrete hormones, they may secrete hormones, they may secrete beta-HCG. We have studied 3 cases of disgerminoma that have reached giant dimensions that secrete beta-HCG detected by radiological imaging, which caused a complaint of abdominal pain in the abdomen. Salpingo-oophorectomy was performed in all three cases. In one case, neighboring lymph nodes, peritoneum and counter-ovary were sampled. In one case, once in three weeks, four times treatment of BEP (Bleomycn, Etoposide, Cisplatin) chemotherapy protocol was administered and treatment was provided without harming fertility. In another case, three treatment BEP chemotherapy protocol was planned to administer and two treatment BEP chemotherapy protocol was performed.

Keywords:

Disgerminoma, Childhood,

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