SİNEM İNAL, Nilüfer KURUCA, TOLGA GÜVENÇ, Merve Gizem SEZENER, Arzu FINDIK, KAMİL SERDAR İNAL

Septicemia and Multiple Abscesses Associated with Pantoea agglomerans in a Dog

A 2-year-old Anatolian Shepherd Dog was presented with lethargy and small abrasion wound on the left paw. The patient was diagnosedwith phlegmon in his left arm and treatment was started. However, septicemia occurred and the dog died after fourteen days. At necropsymultiple white-colored foci was seen on the liver, lungs, kidney and heart. In these organs, abscesses formations with large areas of necrosiswere seen in histopathologic examination. In samples taken from organs with abscess, the bacteria were identified morphologicallyand biochemically by Vitek II and Pantoea agglomerans was confirmed by PCR. Pantoea agglomerans has been previously isolated fromhumans and animals. However, the bacteria is rarely isolated from septicemia associated lesions in animals. In the presented report, Pantoeaagglomerans was identified in a dog with septicemia and clinical, postmortal and histopathological findings caused by the bacteria werereported.

Bir Köpekte Pantoea agglomerans İle İlişkili Septisemi ve Multiple Apse Olgusu

İki yaşlı Anadolu çoban köpeği halsizlik ve sol patide küçük abrazyon yarası şikayetiyle getirildi. Hastanın sol ön kolunda bulanan yaraya fl egmon tanısı konuldu ve tedaviye başlandı. Ancak septisemi meydana geldi ve tedavinin 14. gününde hasta öldü. Nekropside, karaciğer, akciğer, böbrek ve kalpte çok sayıda beyaz renkli odak görüldü. Bu organların histopatolojik incelemesinde, apse yapıları ile geniş nekroz alanları belirlendi. Organlardaki apselerden alınan örneklerde, bakteri morfolojik olarak ve Vitek II ile biyokimyasal olarak identifiye edildi. PCR ile etkenin Pantoea agglomerans olduğu doğrulandı. Pantoea agglomerans daha önce insanlarda ve hayvanlarda izole edilmiştir. Bununla birlikte bu bakteri, hayvanlarda nadiren septisemi ile ilişkili lezyonlardan izole edilmiştir. Bu olgu sunumunda, septisemili bir köpekte identifiye edilen Pantoea agglomerans’ın neden olduğu klinik, postmortal ve histopatolojik bulgular bildirilmiştir.

PDF

___

1. Gavini F, Mergaert J, Beji A, Mielcarek C, Izard D, Kersters K, De Ley J: Transfer of Enterobacter agglomerans (Beijerinck 1888) Ewing and Fife 1972 to Pantoea gen. nov. as Pantoea agglomerans comb. nov. and description of Pantoea dispersa sp. nov. Int J Syst Evol Microbiol, 39 (3): 337-345, 1989. DOI: 10.1099/00207713-39-3-337

2. Dutkiewicz J, Mackiewicz B, Lemieszek MK, Golec M, Milanowski J: Pantoea agglomerans: A mysterious bacterium of evil and good. Part III. Deleterious effects: Infections of humans, animals and plants. Ann Agric Environ Med, 23 (2): 197-205, 2016. DOI: 10.5604/12321966.1203878

3. Henker LC, Lorenzett MP, Keller A, Siqueira FM, Driemeier D, Pavarini SP: Fibrinonecrotic placentitis and abortion associated with Pantoea agglomerans infection in a mare. J Equine Vet Sci, 92:103156, 2020. DOI: 10.1016/j.jevs.2020.103156

4. Pomorski Z, Dutkiewicz J, Taszkun I, Woźniak M, Sitkowski W, Skórska C, Cholewa G: Studies on allergic conditioning of cattle pneumopathy, resulting from breathing in pneumoallergens comprised in organic dusts. Ann Univ Mariae Curie Sklodowska Med, 48, 183-193, 1993.

5. Decuadro A, Ruiz N, Martino P, Sala T, Benech A: Neumonía en gato causada por Enterobacter (Pantoea) agglomerans, reporte de un caso clínico. Veterinaria (Montev), 51 (198): 26-31, 2015.

6. Loch TP, Faisal M: Isolation of Pantoea agglomerans from brown trout (Salmo trutta) from Gilchrist Creek, Michigan, USA. Bull Eur Assoc Fish Pathol, 27 (5): 200-204, 2007.

7. Saticioglu IB, Duman M, Altun S: Antimicrobial resistance and molecular characterization of Pantoea agglomerans isolated from rainbow trout (Oncorhynchus mykiss) fry. Microb Pathog, 119, 131-136, 2018. DOI: 10.1016/j.micpath.2018.04.022

8. Roberts DE, McClain HM, Hansen DS, Currin P, Howerth EW: An outbreak of Klebsiella pneumoniae infection in dogs with severe enteritis and septicemia. J Vet Diagn Invest, 12 (2): 168-173, 2000. DOI: 10.1177/104063870001200215

9. Alobaidi LAH: Isolation, identification, and molecular detection of Pantoea agglomerans from nuts in commercial markets in Al Samawa City. J Int Acad Res Multidiscip, 2 (6): 235-241, 2014.

10. Demircan E, Kasap Demir B, Şahin H, Bayram A, Kanık A: Pantoea agglomerans as a cause of foreign body related septic arthritis in a child: Case report and review of the literature. J Pediatr Infect Dis, 15 (5): 265-268, 2020. DOI: 10.1055/s-0040-1709701

11. Jain S, Bohra I, Mahajan R, Jain S, Chugh T: Pantoea agglomerans infection behaving like a tumor after plant thorn injury: An unusual presentation. Indian J Pathol Microbiol, 55 (3): 386-388, 2012. DOI: 10.4103/0377-4929.101754

12. Seok S, Jang YJ, Lee SW, Kim HC, Ha GY: A case of bilateral endogenous Pantoea agglomerans endophthalmitis with interstitial lung disease. Korean J Ophthalmol, 24 (4): 249-251, 2010. DOI: 10.3341/ kjo.2010.24.4.249

13. Williams AJK, Scott RJD, Lightfoot NF: Erwinia herbicola as a cause of bacterial endocarditis. J Infect, 12, 71-73, 1986. DOI: 10.1016/s0163- 4453(86)94978-9

14. Vincent K, Szabo RM: Enterobacter agglomerans osteomyelitis of the hand from a rose thorn. A case report. Orthopedics, 11 (3): 465-467, 1988.