DUYGU DALĞIN, YÜCEL MERAL, METİN ÇENESİZ

Risperidone as a Promising Treatment of Choice in Dog Owner Directed Aggression

Sahibine yönelik agresyon, en sık gözlenen agresyon vakalarındandır. Agresif davranış biçiminin altında yatan faktörlerden bazıları, sosyalizasyon dönemi tamamlanmadan anneden ayrılma, genetik ve herediter parametreler, aile içi çiftleşme, çevre, aşırı cezalandırma, cinsiyet, yaş, büyüklük, somatik nedenler, çevresel tehditler ve sahip kaynaklı nedenlerdir. Agresif köpek sahiplerinin çözümü genellikle ötenazi veya hayvanı terk etmek olmaktadır. Bu çalışmanın amacı, sahibe yönelik agresyon gösteren köpeklerde risperidon'un (atipik antipsikotik) tehlike riski üzerindeki etkilerini ortaya koymaktır. Agresif davranış şikayeti ile getirilen farklı yaş, cinsiyet ve ırktan 16 ev köpeği, muayeneleri ve fiziksel nedenlerin eliminasyonunu takiben tehlike ve yaralanma riskinin belirlenmesi kriterleri bazında hasta sahibi ile birlikte skorlanmışlardır. Tedavi, hasta sahibinin genel ve davranışsal yaklaşım açısından bilgilendirilmesi ile Risperdal oral solüsyon 1 mg/1 mL, 100 mL sid (1 mg/m2) kullanımı ile şekillendirilmiştir. Muayene, anamnez ve skorlama işlemleri 1 aylık tedaviyi takiben tekrarlanmıştır. Risperidonun, tehlike riskini düşürmede etkin sonuçlar sağladığı ortaya konmuştur. Bu sonuç aynı zamanda pek çok ev köpeğininde terk edilme ve ötenaziden uzak tutulmasına neden olacaktır

Köpeklerde Sahibine Yönelik Agresyonda Başarı Vaad Eden Bir Tedavi Seçeneği Olarak Risperidon

Owner-directed aggression is reported as the most frequent of the aggression cases observed. Some factors underlying aggressive behavior are, adopting before the end of socialization period, genetic and hereditary parameters, inbreeding, environment, excessive punishment, sex, age, size, somatic reasons, territorial threats and owner dependant factors. The choices to deal with aggressive dogs is usually limited by relinquishment or euthanasia. The aim of this study is to evaluate the effects of risperidone (atypical antipsychotic) in decreasing the risk of danger in dogs presenting owner directed aggression. Sixteen household dogs from various age, sex and breed with the complaint of showing aggressive behavior were examined and after elimination of somatic reasons a scoring scale based on the considerations for assessing danger and risk of injury was prepared with the owner. Treatment was comprised of owner informing on the management and behavioral approach for each individual case and medical treatment with Risperdal oral solution 1 mg/1 mL,100 mL sid (1 mg/m2). Examination, history taking and scoring were repeated after 1 month of therapy. Risperidone created satisfactory results in decreasing the risk of danger, also will prevent many household dogs from relinquishment or euthanasia

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1. Fatjo J, Amat M, Mariotti VM, Torre JLR, Manteca X: Analysis of 1040 cases of canine aggression in a referral practice in Spain. J Vet Behav, 2, 158-165, 2007. DOI: 10.1016/j.jveb.2007.07.008
2. Clarke NM, Fraser D: Animal control measures and their relationship to thereported incidence of dog bites in urban Canadian municipalities. Can Vet J, 54, 145-149, 2013.
3. Beaver B: Canine Behavior: A Guide for Veterinarians. Saunders, St. Louis, 137-199, 1999.
4. WHO: Animal bites. In, Media Centre, Fact Sheet. N373, February, 2013.
5. Duffy DL, Hsu Y, Serpell JA: Breed differences in canine aggression. Appl Anim Behav Sci, 114, 441-460, 2008. DOI: 10.1016/j.applanim.2008.04.006
6. Rodrigues R, Polo G, Castagna C, Presotto D, Baldini M, Pisciotta K, Lantzman M, Dias RA: Caracterização de casos de agressão canina em Campinas, São Paulo, Brasil. Braz J Vet Res Anim Sci, 50, 233-237, 2013. DOI: 10.11606/issn.1678-4456.v50i3p233-237
7. Reisner IR, Shofer FS, Nance ML: Behavioral assessment of childdirected canine aggression. Inj Prev, 13, 348-351, 2007. DOI: 10.1136/ ip.2007.015396
8. Oliveira VR, Pereira P, Silva J, Miranda CF, Rodrigues KO, Rodrigues TO, Moreira EC: Mordedura canina e atendimento antirra bico humano em Minas Gerais. Arq Bras Med Vet Zoo, 64, 891-898, 2012. DOI: 10.1590/ S0102-09352012000400016
9. Cornelissen J, Hopster H: Dog bites in The Netherlands: A study of victims,injuries, circumstances and aggressors to support evaluation of breed specific legislation. Vet J, 186, 292-298, 2010. DOI: 10.1016/j. tvjl.2009.10.001
10. De Keuster T, Lamoureux J, Kahn A: Epidemiology of dog bites: a Belgian experience of canine behaviour and public health concerns. Vet J, 172, 482-487, 2006. DOI: 10.1016/j.tvjl.2005.04.024
11. Rosado B, Garcia-Belenguer S, Leon M, Palacio J: A comprehensive study of dog bites in Spain, 1995-2004. Vet J, 179, 383-391, 2009. DOI: 10.1016/j.tvjl.2008.02.002
12. Polo G, Calderón N, Clothier S, Cassia R, Garcia M: Understanding dog aggression: Epidemiologic aspects in memoriam, Rudy de Meester (1953-2012). J Vet Behav, 10, 525-534, 2015. DOI: 10.1016/j.jveb.2015.09.003
13. Pérez-Guisado J, Muñoz-Serrano A: Factors linked to dominance aggression in dogs. J Anim Vet Adv, 8, 336-342, 2009.
14. Casey RA, Loftus B, Bolster C, Richards GJ, Blackwell EJ: Human directed aggression in domestic dogs (Canis familiaris): Occurrence in different contexts and risk factors, Appl Anim Behav Sci, 152, 52-63, 2014. DOI: 10.1016/j.applanim.2013.12.003
15. Bompadre G, Cinotti S: Managing behavioural problems in humandog interactions. Ann Ist Super Sanità, 47, 378-383, 2011. DOI: 10.4415/ Ann_11_04_09
16. Landsberg GM, Hunthausen W, Ackerman L: Handbook of Behavior Problems of the Dog and Cat. 3rd edn., 166, 358-359, 420. Saunders, Elsevier Health Sciences, Missuri, 2012.
17. Beata CA: Diagnosis and Treatment of Aggression in Dogs and Cats Recent Advances in Companion Animal Behavior Problems, Houpt KA (Ed): International Veterinary Information Service, Ithaca NY (www.ivis. org), Last updated: 23-Dec-2001; A0808.1201
18. Vermeire S, Audenaert K, De Meester R, Vandermeulen E, Waelbers T, De Spiegeleer B, Eersels J, Dobbeleir A, Peremans K: Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder. Psychiatry Res, 201, 78-87, 2012. DOI: 10.1016/j.pscychresns.2011.06.006
19. Guy NC, Luescher UA, Dohoo SE, Spangler E, Miller JB, Dohoo IR, Bate LA: Risk factors for dog bites to owners in a general veterinary caseload. Appl Anim Behav Sci, 74, 29-42, 2001. DOI: 10.1016/S0168- 1591(01)00154-X
20. Reisner IR: National survey of owner-directed aggression in English Springer Spaniels. JAVMA, 227, 1594-1603, 2005. DOI: 10.2460/javma. 2005.227.1594
21. Arhant C, Bubna-Littitz H, Bartels A, Futschik A, Troxle J: Behaviour of smaller and larger dogs: Effects of training methods, inconsistency of owner behaviour and level of engagement in activities with the dog. Appl Anim Behav Sci, 123, 131-142, 2010. DOI: 10.1016/j.applanim. 2010.01.003
22. Svartberg K: Breed-typical behaviour in dogs - Historical remnants or recent constructs? App Anim Behav Sci, 96, 293-313, 2006. DOI: 10.1016/j. applanim.2005.06.014
23. Lindsay SR: Handbook of Applied Dog Behavior and Training. Vol. 2, p.166, Blackwell, 2001.
24. Kubinyi E, Turcsán B, Miklósi Á: Dog and owner demographic characteristics and dog personality trait associations. Behav Procc, 81, 392-401, 2009. DOI: 10.1016/j.beproc.2009.04.004
25. Bamberger M, Houpt KA: Signalment factors, comorbidity, and trends in behavior diagnoses in dogs: 1.644 cases (1991-2001). JAVMA, 229, 1591-1601, 2006. DOI: 10.2460/javma.229.10.1591
26. APBC Annual Review of Cases: Canine dominance revisited. http:// www.apbc.org.uk/news_items/review_2005.htm2005; Accessed: 19.01.2017
27. Cakiroğlu D, Meral Y, Sancak AA, Cifti G: Relationship between the serum concentrations of serotonin and lipids and aggression in dogs. Vet Rec, 161, 59-61, 2007. DOI: 10.1136/vr.161.2.59
28. Yalcın E, Yilmaz Z, Ozarda Y: Serum leptin and ghrelin levels and their relationship with serum cortisol, thyroid hormones, lipids, homocysteine and folic acid in dogs with compulsive tail chasing. Kafkas Univ Vet Fak Derg, 23 (2): 227-232, 2017. DOI: 10.9775/kvfd.2016.16334
29. Bennett PC, Rohlf VI: Owner-companion dog interactions: Relationships between demographic variables, potentially problematic behaviours, training engagement and shared activities. Appl Anim Behav Sci, 102, 65, 2007. DOI: 10.1016/j.applanim.2006.03.009
30. Kobelt AJ, Hemsworth PH, Barnett JL, Coleman GJ: A survey of dog ownership in suburban Australia-conditions and behaviour problems. Appl Anim Behav Sci, 82, 137-148, 2003. DOI: 10.1016/S0168- 1591(03)00062-5
31. Bradshaw JWS, Blackwell EJ, Casey RA: Dominance in domestic dogs - Useful construct or bad habit? J Vet Behav Clin Appl Res, 4, 135-144, 2009. DOI: 10.1016/j.jveb.2008.08.004
32. Bradshaw JWS, Casey RA: Anthropomorphism and anthropocentrism in the assessment of quality of life in dogs. Anim Welf, 16, 149- 154, 2007.
33. Blackwell EJ, Twells C, Seawright A, Casey RA: The relationship between training methods and the occurrence of behaviour problems, as reported by owners, in a population of domestic dogs. J Vet Behav, 3, 207-217, 2008. DOI: 10.1016/j.jveb.2007.10.008
34. Ader M, Kim SP, Catalano KJ, Ionut V, Hucking K, Richey JM, Kabir M, Bergman RN: Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: A placebo-controlled study of olanzapine and risperidone in dogs. Diabetes, 54 (3): 862-871, 2005. DOI: 10.2337/diabetes.54.3.862