GÖZDE YÜCEL TENEKECİ, Mehtap ÖZTEKİN, MEHMET FATİH BOZKURT, AYLİN SEPİCİ DİNÇEL, İbrahim Ayhan ÖZKUL

Pathomorphological and Immunohistochemical Studies of Tumours in the Urinary Bladders of Water Buffalo in Marmara, the Central and Western Black Sea Region of Turkey

Çalışmada, Marmara, Orta ve Batı Karadeniz Bölgelerinde bulunan mandaların idrar keselerinde saptanan neoplazik ve neoplazik olmayan bulgular değerlendirildi. Orta, Batı Karadeniz ve Marmara Bölgelerindeki bazı illerde bulunan özel ve kamu kurumu mezbahalarında kesilen mandaların idrar keselerinde rastlanılan lezyonlar patolojik ve immunohistokimyasal yönden incelendi. Ayrıca hastalığın bulunduğu bölgelerdeki hayvanların otladıkları yerlerde doğal olarak yetişen eğrelti otları toplanarak tür teşhisi yapıldı. Çalışma sonucunda toplanan idrar keselerinin histolojik incelenmesinde; otuzdokuz adet neoplazi görüldü. Bu neoplazilerin tanısı Dünya Sağlık Teşkilatı'nın 2004 yılındaki tümör klasifikasyonuna göre yapıldı. Histolojik incelemelerde; otuzdokuz adet neoplazik idrar keselerinin onaltı adeti papillom; yedi adeti düşük malignite potansiyelli papiller ürotelyal neoplazi, onüç adeti düşük dereceli papiller karsinom, iki tanesi yüksek dereceli papiller karsinom ve bir tane ise hemangiosarkom görülmüştür. Düşük dereceli papiller karsinom görülen idrar keselerinden bir tanesinde aynı zamanda hemangiosarkoma da rastlandı. Çalışma sonucunda toplanan eğrelti otlarında ise; Athyrium filix-foemina (L.) Roth; Dryopteris dilatata (Hoffm.) Gary; Dryopteris filix-mas (L.) Schott; Polystichum aculeatum (L.) Roth; Polystichum setiferum (Forsk.) Woynar; Polystichum woronowii Fomin; Polypodium vulgare L. ve Pteridium aquilinum (L.) Kuhn türleri saptandı. Sonuç olarak, manda idrar keselerinde türleri tayin edilen eğrelti otlarının tüketilmesiyle daha çok epitelyal neoplazilerin tetiklendiği anlaşılmıştır

Türkiye’de Marmara, Orta ve Batı Karadeniz Bölgelerinde Bulunan Mandaların İdrar Keselerinde Rastlanılan Tümörlerin Patomorfolojik ve İmmunohistokimyasal Yönden İncelenmesi

In this study, non-neoplastic and neoplastic lesions in the urinary bladders of water buffalo were determined in the Marmara, the central and western part of the Black Sea region of Turkey. In this context, water buffalo with lesions in the urinary bladder were obtained from the private and public slaughterhouses of several provinces. The lesions were evaluated pathologically and immunohistochemically. In addition, species of bracken ferns were identified in these provinces. Histopathologically, 39 of the collected tissue samples were diagnosed as neoplasia. These neoplasms were classified and graded according to The World Health Organization Classification of Tumours published in 2004. In this context, papilloma (16 cases), papillary urothelial neoplasm of low malignant potential (PUNLMP) (7 cases), low-grade papillary carcinoma (13 cases), high-grade papillar carcinoma (2 cases), and low-grade papillary carcinoma with hemangiosarcoma (1 case) were detected in samples diagnosed as neoplasia. In the collected bracken ferns, Athyrium filix-foemina (L.) Roth; Dryopteris dilatata (Hoffm.) Gary; Dryopteris filixmas (L.) Schott; Polystichum aculeatum (L.) Roth; Polystichum setiferum (Forsk.) Woynar; Polystichum woronowii Fomin, Polypodium vulgare L. and Pteridium aquilinum (L.) Kuhn spp. were identified. As a result, it has been understood that the consumption of identified bracken ferns leads more frequently to epithelial neoplasms

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