İvermektin’in sığır deri papillomatozisinde tedavi etkinliği

Bu çalışmada sığır deri papillomatozisinin tedavisinde uzun etkili ivermektin’in etkinliği araştırıldı. Çalışmanın materyalini, 736 aylık, farklı ırk ve cinsiyette, klinik ve histopatolojik olarak papillomatozis teşhisi konulan 24 sığır oluşturdu. Çalışmaya alınan hayvanlar deneme (I. grup) ve kontrol (II. grup) olmak üzere 2 gruba ayrıldı. Deneme grubuna (n=16) 0.2 mg/kg dozda deri altı yolla tek doz uzun etkili ivermektin uygulandı. Kontrol grubuna (n=8) ise herhangi bir uygulama yapılmadı. Çalışmaya alınan bütün hayvanların kontrolleri iki hafta aralıklarla 90 gün süreyle yapıldı. Uzun etkili ivermektin uygulanan I. gruptaki 16 sığırdan 14’ünün (%87.5) 30 ile 90 gün arasında iyileştiği belirlendi. Kontrol grubundaki hayvanlarda ise iyileşme olmadığı görüldü. Sonuç olarak; sığır deri papillomatozisi’nin sağaltımında tek doz, uzun etkili ivermektinin %87,5 oranında etkili olduğu belirlendi.

Anahtar Kelimeler:

ivermektin, sığır papilloma virüsü, sığır, hastalık kontrolü, ilaç tedavisi

Effects of ivermectin on bovine cutaneous papillomatosis

In the present study the effectiveness of long action ivermectin on the treatment of bovine cutaneous papillomatosis was evaluated. Twenty-four cattle with different ages (7-36 months of age), breed and sex with cutaneous papillomatosis were placed into two groups. Long action ivermectin at a dose of 0.2 mg/kg was administered subcutaneously as a single dose to the animals in Group I (experimental group; n=16). Group II (n=8) served as a control group and received no treatment. Animals were monitored at 15 days intervals up to 90 days. In Group II, 14 of 16 animals (87.5%) showed complete recovery within three months of observation period. No remission was observed in the control group. In conclusion ivermectin, as single long action dose application, is effective for the treatment of bovine cutaneous papillomatosis.

Keywords:

ivermectin, bovine papillomavirus, cattle, disease control, drug therapy,

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