Tanveer AHMAD, Muhammad Saleem AKHTAR, Muhammad Mazhar AYAZ, Muhammad mudassar NAZIR, Ejaz AHMAD, Muhammad raza HAMEED, Maqbool HUSSAIN

Insect Bite Hypersensitivity (Sweet Itch) in a Non-Descript Riding Local Breed Mare

Summer itch or insect bite hypersensitivity is common problem during summer in all animals. Some horses are allergic to insect saliva. A 13 year old mare kept for riding purpose at livestock farm FVS, BZU, Multan was examined with a condition characterized by little bumps, papules and abrasions on neck, abdomen, thighs and tail, anaemic mucous membranes, concentrated urine, partial anorexia and generalized emaciation. There was a history of chronic lesion of about more than one year old and many therapies were tried but all non-responsive. A mixed biting infection of Tabanus spp. and Stomoxys spp. was identified. On the basis of clinical sign(s), history and fly identification a diagnosis of insect bite hypersensitivity was detected. Treatment protocol was done in two rounds i.e. first round of treatment was done with dexamethasone along & vitamin E administrated through intramuscular route for 5 days and followed by 10 mg dexamethasone orally for one month. Animal respond the treatment and there was full recovery from condition and on follow up no relapse of the condition was observed.

Yerel Irk Bir Kısrakta Böcek Sokmasına Bağlı Aşırı Duyarlılık (Tatlı Kaşıntı)

Yaz kaşıntısı veya böcek sokması aşırı duyarlılığı tüm hayvanlarda yaz aylarının yaygın bir problemidir. Bazı atlar böcek salyasına alerjiktir. FVS, BZU, Multan’da bir çiftlikte binek amaçlı tutulan 13 yaşlı bir kısrakta boyun, abdomen, uyluk ve kuyrukta küçük şişkinlikler, papüller ve abrazyonlar, anemik mukoz membranlar, konsantre idrar, kısmi iştah kaybı ve generalize zayıflama bulguları gözlemlendi. Yaklaşık bir yıldan daha uzun süredir devam eden kronik lezyon tablosu olup birçok tedavi uygulanmış ancak hepsi cevapsız kalmıştı. Tabanus spp. ve Stomoxys spp.’nin her ikisinin sokmasına bağlı enfeksiyon belirlendi. Klinik bulgular, hastalık hikâyesi ve sinek tespit edilmesine dayanarak böcek sokması aşırı duyarlılığı tanısı koyuldu. Tedavi iki basamaklı olarak gerçekleştirildi. Birinci basamakta 5 gün dekzametazon ile birlikte kasiçi vitamin E uygulaması yapılırken ikinci basamakta 10 mg dekzametazon oral yolla bir ay uygulandı. Hayvan tedaviye yanıt vererek hastalığı tamamen atlattı ve takipte hastalık tekrarı gözlenmedi.

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1. Wirtz RA: Allergic and toxic reactions to non-stinging arthropods. Annu Rev Entomol, 29 (1): 47-69, 1984. DOI: 10.1146/annurev.en.29.010184.000403

2. Schaffartzik A, Hamza E, Janda J, Crameri R, Marti E, Rhyner C: Equine insect bite hypersensitivity: What do we know? Vet Immunol Immunopathol, 147 (3-4): 113-126, 2012. DOI: 10.1016/j.vetimm.2012. 03.017

3. Lanz S, Brunner A, Graubner C, Marti E, Gerber V: Insect bite hypersensitivity in horses is associated with airway hyperreactivity. J Vet Intern Med, 31 (6): 1877-1883, 2017. DOI: 10.1111/jvim.14817

4. Peeters LM, Janssens S, Brebels M, Buys N: Genetic parameters and estimated breeding values of insect bite hypersensitivity in Belgian Warmblood horses. Vet J, 206 (3): 420-422, 2015. DOI: 10.1016/j.tvjl. 2015.08.012

5. Yi L, Cheng D, Zhang K, Huo X, Mo Y, Shi H, Di H, Zou Y, Zhang H, Zhao J, Xu Y, Erle DJ, Zhen G: Intelectin contributes to allergeninduced IL-25, IL-33 and TSLP expression and type 2 response in asthma and atopic dermatitis. Mucosal Immunol, 10 (6): 1491-1503, 2017. DOI: 10.1038/mi.2017.10

6. Lukschal A, Wallmann J, Bublin M, Hofsetter G, Mothes-Luksch N, Breiteneder H, Pali-Schöll I, Jensen-Jarolim E: Mimotopes for Ap g 5, a relevant cross-reactive allergen, in the celery-mugwort-birchspice syndrome. Allergy Asthma Immunol Res, 8 (2): 124-131, 2016. DOI: 10.4168/aair.2016.8.2.124

7. Gershwin LJ: Comparative immunology of allergic responses. Annu Rev Anim Biosci, 3 (1): 327-346, 2015. DOI: 10.1146/annurev-animal022114-110930

8. Marsella R: Equine allergy therapy: Update on the treatment of environmental, insect bite hypersensitivity, and food allergies. Vet Clin North Am: Equine Pract, 29 (3): 551-557, 2013. DOI: 10.1016/j.cveq.2013.08.006

9. Wilson AD, Harwood LJ, Bjornsdottir S, Marti E, Day MJ: Detection of IgG and IgE serum antibodies to Culicoides salivary gland antigens in horses with insect dermal hypersensitivity (sweet itch). Equine Vet J, 33 (7): 707-713, 2001. DOI: 10.2746/042516401776249363

10. de Raat IJ, van den Boom R, van Poppel M, van OldruitenborghOosterbaan MM: The effect of a topical insecticide containing permethrin on the number of Culicoides midges caught near horses with and without insect bite hypersensitivity in the Netherlands. Tijdschr Diergeneeskd, 133 (20): 838-842, 2008.

11. Schurink A, van Grevenhof EM, Ducro BJ, van Arendonk JAM: Heritability and repeatability of insect bite hypersensitivity in Dutch Shetland breeding mares. J Anim Sci, 87 (2): 484-490, 2009. DOI: 10.2527/ jas.2008-1129

12. Baker KP, Quinn PJ: A report on clinical aspects and histopathology of sweet itch. Equine Vet J, 10 (4): 243-248, 1978. DOI: 10.1111/j.2042- 3306.1978.tb02271.x

13. Wagner B, Childs BA, Erb HN: A histamine release assay to identify sensitization to Culicoides allergens in horses with skin hypersensitivity. Vet Immunol Immunopathol, 126 (3-4): 302-308, 2008. DOI: 10.1016/j. vetimm.2008.09.001

14. Schurink A, Wolc A, Ducro BJ, Frankena K, Garrick DJ, Dekkers JCM, van Arendonk JAM: Genome-wide association study of insect bite hypersensitivity in two horse populations in the Netherlands. Genet Sel Evol, 44:31, 2012. DOI: 10.1186/1297-9686-44-31