Erkut TÜZER, MUSTAFA NECATİ MUZ, ZAHİDE BİLGİN, Süleyman ERÇİN, Recep TINAR

Fipronil damlatma çözeltisinin kedi ve köpeklerde pirelere ve köpeklerde kenelere etkisi

Bu çalışmada Türkiye’de daha önce etkisi denenmemiş olan fipronilin doğal enfeste olan kedilerde pirelere (Ctenocephalides felis, Ct. canis) ve köpeklerde pire (Ct. canis, Ct. felis, Pulex irritans) ve kenelere (Rhipicephalus sanguineus) karşı etkisi değerlendirilmiştir. Fipronil damlatma çözeltisi (Spotline®, TOPKİM İlaç Sanayi AŞ), 0.067 ml/kg (6.7 mg aktif madde/kg) dozu esas alınarak pratik uygulama dozlarında, omuz bölgesinde, kıllar ayrılarak, iki ayrı noktaya, deriye temas edecek şekilde damlatılarak uygulanmıştır. Tedaviden sonra hayvanlar birkaç gün (3-5 gün) ektoparazit yönünden incelenmiştir. İlaç etkisi, tedavi sonrasında hayvanların parazitten tamamen arınma oranına göre hesaplanmıştır. Fipronil, kedi (15 kedi) ve köpeklerde (16 köpek) pireleri ve köpeklerde (12 köpek) keneleri öldürerek ve/veya uzaklaştırarak %100 etkili bulunmuştur. Tedaviden sonra, yoğun pire enfestasyonu görülen yavru köpeklerle bir araya konulan bir köpekte 9 gün boyunca renfestasyon ve arkasından ölüm sonucu yoğunluğu giderek azalan canlı ve ölü pireler görülmüştür. İlacın hayvanlarda olumsuz bir etkisi gözlenmemiştir.

Anahtar Kelimeler:

Ctenocephalides canis, Ctenocephalides felis, Pulex irritans, Rhipicephalus sanguineus, kedi, köpek

Efficacy of Fipronil spot on against fleas on cats and dogs and ticks on dogs

Efficacy of fipronil, which until now has not been assessed in Turkey, was tested against fleas (Ctenocephalides felis, Ct. canis) on cats and fleas (Ct. canis, Ct. felis, Pulex irritans) and ticks (Rhipicephalus sanguineus) on dogs. Fipronil spot-on (Spotline®, TOPKİM İlaç Sanayi AŞ, Turkey) was applied directly on to the two different skin points between the shoulder blades of animals at recommended practical doses based on the dose of 0.067 ml/kg (6.7 mg active ingredient/kg). Animals were examined for the presence of parasites several days (3-5 days) after treatment. Drug efficacy was calculated from the percentages of animals becoming free of parasites after treatment. Fipronil was 100% effective to remove and/or kill fleas on both dogs (16 dogs) and cats (15 cats) and ticks on dogs (12 dogs). Live and death parasites in decreasing numbers as a result of re-infestation and after dying were seen on a dog for 9 days after treatment, which was put together with heavy flea infested puppies. No adverse reactions were observed in both dogs and cats treated.

Keywords:

Ctenocephalides canis, Ctenocephalides felis, Pulex irritans, Rhipicephalus sanguineus, cats, dogs,

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