Serkan Barış MÜLAZIMOĞLU, Hakkı Bülent BECERİKLİSOY, Sabine SCHAFER-SOMI, Mahir KAYA, ALİ BUMİN, ERHAN ÖZENÇ, NİLGÜN GÜLTİKEN, HALİT KANCA, Münevver Ziynet GÜNEN, Osman KUTSAL, BİRTEN EMRE, Kiossis EVANGELOS, Selim ASLAN

B-mode Echotexture Analysis and Color Doppler Sonography in Canine Mammary Tumors

Çalışma için 28 dişi köpeğe ait olan 41 meme tümörü dokusu kullanılmıştır. Cerrahi eksizyon öncesi tümörlü kitleler B-Mode ultrasonografik muayene ile incelenmiş, görüntüler digital olarak kayıt edilmiş ve ekodesen analizi için bu görüntüler üzerinde rastgele olarak dörtlü inceleme alanları (Region of Interest) seçilmiştir. Tüm tümörlü dokular, cerrahi eksizyon sonrası histopatolojik olarak incelenmiştir. Ultrasonografik resimlerin yapısal analizleri için, Kontrast (CONT), Ortalama Gradyan (MG), Ortalama Değer (MV), Homojenite (HOM), Entropi (ENTR) ve Gri Değer (GV) parametreleri kullanılmıştır. Ultrasonografik resimler ek olarak tümör kitlesi, tümör şekli, tümörün çevre dokulara invazyonu, tümör sınır keskinliği, tümörün ekojenitesi, hiperekojenik artefakt, anekojenik artefakt ve tümör etrafındaki gölgelenme gibi makroskopik parametreler açısından da değerlendirilmiştir. B-Mod ultrasonografik muayenenin ardından, renkli Doppler ile Pulzatil İndeks (PI), Rezistif İndeks (RI), Pik Sistolik Akım Hızı (Vmax) ve Renkli Piksel Sayısı (CP) parametreleri değerlendirilmiştir. İstatistiki analizler sonucunda HOM ve GV parametreleri açısından, benign (3.10 ve 1.14) ve malign (1.54 ve 0.57; P

Köpek Meme Tümörlerinde B-Mode Ekodesen Analizi ve Renkli Doppler Ultrasonografi

Forty-one mammary gland tumors from twenty eight bitches were used for the study. Ultrasonographic examinations of tumor masses were performed before surgical excision and a quadratic region-of-interest (ROI) was chosen randomly on B-mode tumor images for the echotexture analyses. All tumors were evaluated histopathologically after surgery. Contrast (CONT), Mean Gradient (MG), Mean Value (MV), Homogeneity (HOM), Entropy (ENTR) and Gray Value (GV) parameters were used for the texture analyses of ultrasonographic images. Ultrasonographic image characteristics were additionally evaluated by the following macroscopic patterns: tumor shape, invasion of tumor to surrounding tissue, tumor border sharpness, echogenicity of tumor, hyperechogenic artifact, anechogenic artifact, and shadow around tumor. After B-mode ultrasonographic examination, Pulsatility Index (PI), Resistive Index (RI), Peak Systolic Flow Velocity (Vmax) and Number of Color Pixel (CP) parameters were evaluated by means of color Doppler sonography. Statistical analysis of the HOM and GV parameters indicated that there was a significant difference between benign (3.10 and 1.14) and malignant tumors (1.54 and 0.57; P<0.01). Besides, a significant difference was found between images of MalignantMixed Tumors (MMT) and Benign-Mixed Tumors (BMT) with regard to CONT and HOM (p< 0.001). In addition, MV was significantly higher in malignant tumors in comparison to the benign cases (P<0.05). A significant negative correlation was found between tumor size and MV in malignant tumor and adenocarcinoma cases (-0.991/ P<0.05; -0.999/P<0.01, respectively). On the other hand, there was a positive correlation between tumor size and GV (0.961/P<0.05) in malignant tumors

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