Lityum Tedavisine Bağlı Gelişen Kalıcı Sere Sendrom: Olgu Sunumu

Bu yazımızda iki uçlu bozukluğu olan 23 yaşındaki birerkek hastada normal aralıktaki serum lityum düzeylerinerağmen kalıcı serebellar sendrom gelişen bir olguyu sunduk. Lityum tedavisi başlanmasından 1 yıl sonra hastadadizartri, ataksi, tremor gibi serebellar bulgular gelişti. 2yıl sonra, hastanın serebellar bulgularının kalıcı olduğugözlendi. Olgumuzda gelişen serebellar sendrom en büyükolasılıkla lityum tedavisiyle birlikte antipsikotik kullanılmasına bağlıdır.

Persistent cerebellar syndrome due to lithium treatment: a case report

We report the case of a 23-year-old man with bipolardisorder who developed permanent cerebellar damage oflithium intake within therapeutic ranges. Cerebellar symptoms such as dysarthria, ataxia, and tremor developed 1year after the beginning of lithium. Two years later, cerebellar signs and symptoms were found to be permanentin the patient. Cerebellar syndrome was most probablydue to lithium neurotoxicity, which was associated withthe administration of antipsychotic.

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