Deliryöz Mani: Klinik Özellikleri ve Tedavisi

Deliryöz mani; mani ve deliryum belirtilerinin birliktegörüldüğü, çoğunlukla katatonik özelliklerin de eşlik ettiğibir sendromdur. Birkaç saat veya gün içerisinde başlar,otonomik belirtiler eşlik edebilir ve tedavi edilmediğitakdirde klinik tablonun ağırlaşması hatta ölümle sonuçlanabilir. Literatürde, maninin bir alt grubu, manik hastalığın ağır formu ve bir katatoni formu olduğu yönündeçeşitli tanımlamaları vardır. Çalışmalarda en etkili tedaviyönteminin EKT olduğu öne sürülse de benzodiyazepinler,duygudurum dengeleyicileri veya birinci ve ikinci kuşakantipsikotikler ile iyileşen olgu bildirimleri mevcuttur. Buyazımızda deliryöz mani tanısı koyduğumuz bir hastanınklinik seyrini anlatarak, bu sendrom hakkında ayrıntılı bilgivermeyi amaçlıyoruz.

Delirious mania: Clinical course and treatment

Delirious mania (DM) is a syndrome consists of both maniaand delirium, generally with accompanying catatonic features. Symptoms occur in hours or days with or withoutautonomic symptoms and if it is not treated properly, theclinical course get worse even it may result with death.It is defined variously in the literature as a subgroup ofmania, a severe form of mania or a catatonioform disease.There are many case reports on the treatment of DMwith benzodiazepines, mood stabilizers or first and sec- ond generation antipsychotics although electroconvulsivetherapy was reported as the most effective treatment. Inthis paper, we aimed to review and give detailed clinicalinformation about DM by presenting clinical course of apatient with delirious mania.

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  • 1. Karmacharya R, England ML, Öngür D. Delirious mania: Clinical features and treatment response. J Affective Disorder. 2008;109:312-6.
  • 2. Bell L. On a form of disease resembling some advanced stage of mania and fever. Am J Insanity. 1849;6:97-127.
  • 3. Weintraub D, Lippmann S. Delirious mania in the elderly. International Journal of Geriatric Psychiatry. 2001;16:374-7.
  • 4. Carlson GA, Goodwin FK, Bethesda, The stages of mania. A longitudinal analysis of the manic episode. Archives of General Psychiatry. 1973;28:221-8.
  • 5. Taylor MA, Abrams R. The phenomenology of mania: a new look at some old patients. Archives of General Psychiatry. 1973;29:520-2.
  • 6. Klerman GL. The spectrum of mania. Comprehensive Psychiatry. 1981;22:11-20.
  • 7. Rajshekhar B, Majeed AK. Delirious mania: Can we get away with this concept? A case report and review of the literature. Case Reports in Psychiatry. 2012;2012:720354.
  • 8. Fink M. Delirious mania. Bipolar Disorders. 1999;1:54-60.
  • 9. Lee BS, Huang SS, Hsu WY, Chiu NY. Clinical features of delirious mania: a series of five cases and a brief literature review. BMC Psychiatry. 2012;12:65-73.
  • 10. Detweiler MB, Mehra A, Rowell T, Kim KY, Bader G. Delirious mania and malignant catatonia: A report of 3 cases and review. Psychiatric Quarterly. 2009;80:23-40.
  • 11. Bobo WV, Murphy MJ, Heckers SH. Recurring episodes of Bell’s Mania after cerebrovascular accident. Psychosomatics. 2009;50:285-8.
  • 12. Bond TC. Recognition of acute delirious mania. Archives of General Psychiatry. 1980;37:553-4.
  • 13. Kimmel SE, Calabrese JR, Woyshville MJ, Meltzer HY. Clozapine in treatment-refractory mood disorders. J Clin Psychiatry. 1994. 55:91-3.
  • 14. Nielsen J, Kane JM, Correll CU. Real-world effectiveness of clozapine in patients with bipolar disorder: results from a 2-year mirror-image study. Bipolar Disorders. 2012;14:863-9.