Recep Tekin, Özben Yalçın, Şirin Menekşe Yılmaz, Yılmaz Arayıcı

Gastrointestinal mucormycosis causing an acute intestinal obstruction in neonate patient

Anahtar Kelimeler:

-

Gastrointestinal mucormycosis causing an acute intestinal obstruction in neonate patient

Neonatal gastrointestinal mucormycosis is a rare, usually fatal, opportunistic fungal infection, which is difficult to diagnose early or preoperatively. Clinically, it may be indistinguishable from the neonatal necrotizing enterocolitis and the diagnosis is usually made on autopsy or histopathology of excised surgical specimen. The treatment should include radical surgical debridement, application of systemic high doses amphotericin B and control of the underlying disease. Herein, we presented a case of neonatal gastrointestinal mucormycosis in a 25 days-old infant. A twenty-five-days-old neonate admitted with the preliminary diagnosis of acute intestinal obstruction that was diagnosed as gastrointestinal mucormycosis and was treated with liposomal amphotericin.

Keywords:

-,

PDF

___

Agarwal K, Sharma M, Singh S, et al. Antemortem diagno- sis of gastrointestinal mucormycosis in neonates: Report of two cases and review of literature. Indian J Pathol Microbiol 2006;49:430–432.
Lee JH, Ha HK, Yoo E, et al. CT and sonographically guided biopsy in a patient with intestinal mucormycosis. AJR Am J Roentgenol 2000;175:129–231.
Pagano L, Offidani M, Fianchi L, et al. Mucormycosis in hema- tologic patients Haematologica 2004;89:207–214.
Kline MW. Mucormycosis in children: review of the literature and report of cases. Pediatr Infect Dis 1985;4:672–676.
Dhingra KK, Mandal S, Khurana N. Unsuspected intestinal mucormycosis in a neonate presenting as necrotizing en- terocolitis (NEC). Eur J Pediatr Surg 2008;18:119–120.
Maravi-Poma E, Rodriguez-Tudela JL, de Jalon JG, et al. Out- break of gastric mucormycosis associated with the use of wooden tongue depressors in critically ill patients. Intensive Care Med 2004;30:724–728.
Sarin YK. Intestinal mucormycosis in a neonate: A case report and review. J Indian Assoc Pediatr Surg 2010;15:98–100.
Ibrahim AS, Spellberg B, Avanessian V, Fu Y, et al. Rhizopus oryzae adheres to, is phagocytosed by, and damages en- dothelial cells in vitro. Infect Immun 2005;73:778-783.
Reimund E, Ramos A. Disseminated neonatal gastrointestinal mucormycosis: A case report and review of the literature. Pe- diatr Pathol 1994;14:385–389.
Michalak DM, Cooney DR, Rhodes KH, et al. Gastrointes- tinal mucormycosis in infants and children: a cause of gan- grenous intestinal cellulitis and perforation. J Pediatr Surg 1980;15:320–324.