Buğra ÇOŞKUN, Ali İrfan GÜZEL, Bora ÇOŞKUN, Demet KOKANALI, Coşkun ŞİMŞİR, Melike DOĞANAY

Myomektomi uygulanan kadınlarda vücut kitle indeksi ile klinik parametreler arasındaki ilişkinin değerlendirilmesi

ÖZAmaç: Abdominal myomektomi uygulanan kadınlarda vücut kitle indeksi ile klinik parametreler arasındaki ilişkiyi korelasyon analizi kullanarak değerlendirmek. Gereç ve Yöntem: Çalışmamıza abdominal myomektomi yapılan toplam 273 kadın dahil edildi. Hastalar vücut kitle indeksi (VKİ) ‘ne göre (≤30 kg / m2 ve > 30 kg / m2) iki gruba ayrıldı. Yaş, VKİ, gravida, parite, myom çapı, preoperatif ve postoperatif hemoglobin (hb) düzeyleri, beyaz kan hücresi ve trombosit sayısı, nötrofil-lenfosit oranı (NLR), Ca125, Ca15-3 , Ca19-9, CEA, AFP düzeyleri, postoperatif hastanede kalış süresi ve postoperatif komplikasyonlar gibi değişkenler retrospektif olarak incelendi. Vücut kitle indeksi ve klinik parametreler arasındaki ilişkiyi değerlendirmek için Pearson korelasyon analizi kullanıldı. Bulgular: Obez grup 64, obez olmayan grup 209 hastadan oluştu. Obez grupta myom boyutu, ameliyat sonrası hb daha düşük, hastanede yatış süresi daha uzun, AFP düzeyi ve komplikasyon varlığı obez olmayan gruba göre daha yüksekti. Korelasyon analizine göre, VKİ ile myom boyutu ve AFP düzeyleri arasında pozitif korelasyon varken; VKİ ile postoperatif hb düzeyi ve hastanede kalış süresi arasında negatif korelasyon vardı. Sonuç: Obezitenin, abdominal myomektomi uygulanan hastaların klinik sonuçlarını olumsuz etkilediğini düşünüyoruz.

Anahtar Kelimeler:

Myom, abdominal myomektomi, obezite, korelasyon analizi

The evaluation of association between body mass index and clinical parameters in women underwent myomectomy

ABSTRACTAim: To evaluate the association between body mass ındex and clinical parameters in women underwent abdominal myomectomy by using correlation analysis. Material and Method: In this retrospective study a total of 273 women underwent abdominal myomectomy during the study period. The patients were classified into two groups according to BMI (≤30 kg/m2 and > 30 kg/m2). Risk factors recorded involved were; age, body mass index (BMI), gravidity, parity, diameter of the fibroid (DOF), preoperative and postoperative hemoglobin (hb) levels, white blood cell and trombocyte count, neutrophil-lymphocyte ratio (NLR), Ca125, Ca15-3, Ca19-9, CEA, AFP levels, duration of postoperative hospital stay and postoperative complications. Pearson correlation analysis was used to evaluate the association between body mass index and clinical parameters. Results: The obese group consisted of 64 patients and the nonobese group consisted of 209 patients. In obese group, DOF was larger postoperative hb was lower, length of hospital stay was longer, level of AFP and the presence of complications was higher than in nonobese group. According to the correlation analysis, there were positive correlation between BMI and DOF and AFP levels, while there were negative correlation between BMI and postoperative hb level and length of hospital stay. Conclusion: We think that obesity adversely affects the clinical outcomes of patients underwent abdominal myomectomy.

Keywords:

Fibroid, abdominal myomectomy, obesity, correlation analysis,

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