On İki Haftalık Ursodeoksikolik Asit ve Sükralfat Kombine Tedavisi ile Semptomları Kaybolan Safra Reflüsü Gastritli İki Adolesan Olgu

Safra reflüsü gastriti veya alkalen reflü gastriti; safra, pankreatik ve intestinal sekresyonların mideye aşırı kaçışına bağlı olarak oluşur. Artmış enterogastrik reflü mide mukozasında hasara yol açabilir. Bu hastalarda asit baskılayıcı tedavilere genellikle yanıt vermeyen dispeptik yakınmalar görülür. Burada proton pompa inhibitörüne (PPI) cevap vermeyen dispeptik yakınmaları nedeni ile üst gastrointestinal sistem endoskopisi yapılan ve alkalen reflü gastriti tanısı alan, on iki haftalık ursodeoksikolik asit ve sükralfat kombine tedavisi ile semptomları kaybolan iki adolesan olgu sunulmuştur.

Anahtar Kelimeler:

Safra reflüsü gastriti, ursodeoksikolik asit, sükralfat, adolesan

Bile reflux gastritis in two adolescant patients, who became asymptomatic with ursodeoxycholic acid and sucralfate combination therapy in twelve weeks.

Bile reflux gastritis or alkaline reflux gastritis is due to an excessive reflux of bile, pancreatic and intestinal secretions into the stomach. Increased enterogastric reflux may cause gastric mucosal injury. These patients have dyspeptic symptoms that generally do not respond to acid suppressing medications. Here, we present two adolescent patients who underwent upper gastrointestinal endoscopy due to dyspeptic symptoms resistant to proton pump inhibitors (PPI) and who were diagnosed as alkaline reflux gastritis and became asymptomatic with ursodeoxycholic acid and sucralfate combination in twelve weeks. Key words: Adolescents, bile reflux gastritis, ursodeoxycholic acid, sucralfate

Keywords:

Adolescents, bile reflux gastritis, ursodeoxycholic acid, sucralfate,

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